The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 94: Probable tyrosine-protein phosphatase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein tyrosine/serine/threonine phosphatase activity GO:0008138
Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
8 P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA)
MAP kinase tyrosine/serine/threonine phosphatase activity GO:0017017
Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.
3 P40479 (/IDA) P40479 (/IDA) Q5APU2 (/IDA)
MAP kinase tyrosine phosphatase activity GO:0033550
Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.
3 O13453 (/IDA) P40479 (/IDA) P40479 (/IDA)
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
1 Q5APU2 (/IDA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inactivation of MAPK activity GO:0000188
Any process that terminates the activity of the active enzyme MAP kinase.
10 P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P40479 (/IMP) P40479 (/IMP)
Inactivation of MAPK activity GO:0000188
Any process that terminates the activity of the active enzyme MAP kinase.
8 P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA)
Inactivation of MAPK activity GO:0000188
Any process that terminates the activity of the active enzyme MAP kinase.
8 P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI)
Adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion GO:0000754
In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.
8 P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI)
Adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion GO:0000754
In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.
8 P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
8 P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
8 P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
8 P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI) P38590 (/IGI)
Regulation of fungal-type cell wall organization GO:0060237
Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
8 P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP)
Regulation of MAPK export from nucleus GO:0071701
Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.
8 P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP) P38590 (/IMP)
Cell wall integrity MAPK cascade GO:0000196
A MAPK cascade that contributes to cell wall organization or biogenesis.
2 P40479 (/IGI) P40479 (/IGI)
Peptidyl-tyrosine dephosphorylation GO:0035335
The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
2 P40479 (/IDA) P40479 (/IDA)
Peptidyl-threonine dephosphorylation GO:0035970
The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
2 P40479 (/IDA) P40479 (/IDA)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 Q5APU2 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q5APU2 (/IMP)
Regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion GO:0010969
Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
1 O13453 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q5APU2 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 Q5APU2 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 Q5APU2 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 Q5APU2 (/IMP)
Negative regulation of MAPK cascade GO:0043409
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
1 O13453 (/EXP)
Negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion GO:0090029
Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
1 Q5APU2 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900435
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1 Q5APU2 (/IMP)
Negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900444
Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1 Q5APU2 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
11 O13453 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P40479 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P38590 (/IDA) P40479 (/IDA) P40479 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P38590 (/HDA) P38590 (/HDA) P38590 (/HDA) P38590 (/HDA) P38590 (/HDA) P38590 (/HDA) P38590 (/HDA) P38590 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O13453 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O13453 (/HDA)
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