The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Protein tyrosine phosphatase superfamily
".
FunFam 82: Serine/threonine/tyrosine-interacting-like protein...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pseudophosphatase activity GO:0001691
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Pseudophosphatase activity GO:0001691
Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
|
2 | Q9Y6J8 (/IMP) Q9Y6J8 (/IMP) |
|
Protein phosphatase inhibitor activity GO:0004864
Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
|
2 | Q9Y6J8 (/IDA) Q9Y6J8 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9Y6J8 (/IPI) Q9Y6J8 (/IPI) |
|
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
|
2 | Q9Y6J8 (/IPI) Q9Y6J8 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Negative regulation of phosphoprotein phosphatase activity GO:0032515
Any process that stops or reduces the activity of a phosphoprotein phosphatase.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Negative regulation of stress granule assembly GO:0062030
Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Regulation of intrinsic apoptotic signaling pathway GO:2001242
Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
2 | Q9Y6J8 (/IMP) Q9Y6J8 (/IMP) |
|
Negative regulation of phosphoprotein phosphatase activity GO:0032515
Any process that stops or reduces the activity of a phosphoprotein phosphatase.
|
2 | Q9Y6J8 (/IDA) Q9Y6J8 (/IDA) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | Q9Y6J8 (/TAS) Q9Y6J8 (/TAS) |
|
Negative regulation of stress granule assembly GO:0062030
Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
|
2 | Q9Y6J8 (/IMP) Q9Y6J8 (/IMP) |
|
Regulation of intrinsic apoptotic signaling pathway GO:2001242
Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
2 | Q9Y6J8 (/IGI) Q9Y6J8 (/IGI) |
|
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
|
2 | Q9Y6J8 (/IMP) Q9Y6J8 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | D3YZ02 (/ISO) Q9DAG7 (/ISO) Q9DAR2 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q9Y6J8 (/IDA) Q9Y6J8 (/IDA) |
