The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Protein tyrosine phosphatase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115: Tyrosine-protein phosphatase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein tyrosine phosphatase activity GO:0004725
Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
7 P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P32587 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P25044 (/IPI) P25044 (/IPI) P25044 (/IPI) P25044 (/IPI) P25044 (/IPI) P25044 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Invasive growth in response to glucose limitation GO:0001403
A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
6 P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
6 P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P25044 (/IDA) P25044 (/IDA)
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
6 P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP)
Pseudohyphal growth GO:0007124
A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
6 P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP) P25044 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P32587 (/IC)
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
1 P32587 (/IC)
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
1 P32587 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 P25044 (/HDA) P25044 (/HDA) P25044 (/HDA) P25044 (/HDA) P25044 (/HDA) P25044 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 P25044 (/HDA) P25044 (/HDA) P25044 (/HDA) P25044 (/HDA) P25044 (/HDA) P25044 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P32587 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P32587 (/HDA)
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