The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Adenylosuccinate Synthetase, subunit A, domain 3
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Adenylosuccinate synthetase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 19 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
188 P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI) P0A7D4 (/IPI)
(178 more)
Adenylosuccinate synthase activity GO:0004019
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
187 D4AEP0 (/IDA) M0R629 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA)
(177 more)
Adenylosuccinate synthase activity GO:0004019
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
30 A4Z6H0 (/ISS) A5PJR4 (/ISS) Q561L1 (/ISS) Q561L1 (/ISS) Q68F20 (/ISS) Q68F20 (/ISS) Q6DIW6 (/ISS) Q6NSN5 (/ISS) Q8EHG3 (/ISS) Q8IDF6 (/ISS)
(20 more)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
14 Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS)
(4 more)
Adenylosuccinate synthase activity GO:0004019
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
5 P80210 (/IMP) P80210 (/IMP) P80210 (/IMP) P80210 (/IMP) Q8N142 (/IMP)
DNA replication origin binding GO:0003688
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
4 P80210 (/IDA) P80210 (/IDA) P80210 (/IDA) P80210 (/IDA)
Adenylosuccinate synthase activity GO:0004019
Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
4 P28650 (/ISO) P28650 (/ISO) P46664 (/ISO) P46664 (/ISO)
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
3 P30520 (/NAS) P30520 (/NAS) Q8N142 (/NAS)
Phosphate ion binding GO:0042301
Interacting selectively and non-covalently with phosphate.
3 P30520 (/NAS) P30520 (/NAS) Q8N142 (/NAS)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
2 P28650 (/ISO) P28650 (/ISO)
Showing 1 to 10 of 19 entries

There are 37 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Purine nucleotide biosynthetic process GO:0006164
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
175 P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP)
(165 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
170 P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP) P0A7D4 (/IEP)
(160 more)
Nucleobase-containing small molecule interconversion GO:0015949
The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
170 P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA)
(160 more)
Adenosine biosynthetic process GO:0046086
The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
170 P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP) P0A7D4 (/IMP)
(160 more)
Purine nucleotide biosynthetic process GO:0006164
The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
15 P21900 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS)
(5 more)
AMP biosynthetic process GO:0006167
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
14 Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS) Q8IDF6 (/ISS)
(4 more)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
8 Q8EHG3 (/ISS) Q9KNX8 (/ISS) Q9KNX8 (/ISS) Q9KNX8 (/ISS) Q9KNX8 (/ISS) Q9KNX8 (/ISS) Q9KNX8 (/ISS) Q9KNX8 (/ISS)
AMP biosynthetic process GO:0006167
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
5 P30520 (/IDA) P30520 (/IDA) P46664 (/IDA) P46664 (/IDA) Q8N142 (/IDA)
AMP biosynthetic process GO:0006167
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
4 P28650 (/ISO) P28650 (/ISO) P46664 (/ISO) P46664 (/ISO)
Aspartate metabolic process GO:0006531
The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
4 P28650 (/ISO) P28650 (/ISO) P46664 (/ISO) P46664 (/ISO)
Showing 1 to 10 of 37 entries

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
175 A0A024R5Q7 (/IDA) A0A024R5Q7 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA) P0A7D4 (/IDA)
(165 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
171 P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA)
(161 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
170 P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA) P0A7D4 (/HDA)
(160 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P30520 (/TAS) P30520 (/TAS) P46664 (/TAS) P46664 (/TAS) Q8N142 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P80210 (/HDA) P80210 (/HDA) P80210 (/HDA) P80210 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A024R5Q7 (/IDA) A0A024R5Q7 (/IDA) P30520 (/IDA) P30520 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P28650 (/IDA) P28650 (/IDA) Q8N142 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P28650 (/ISO) P28650 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P46664 (/ISO) P46664 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P46664 (/ISO) P46664 (/ISO)
Showing 1 to 10 of 17 entries
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