The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Glycosyl transferase family 29
".
FunFam 1: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltra...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity GO:0003828
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
|
17 |
O35696 (/IDA)
O43173 (/IDA)
Q64689 (/IDA)
Q64692 (/IDA)
Q64692 (/IDA)
Q92186 (/IDA)
Q92186 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
(7 more) |
|
Sialic acid binding GO:0033691
Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
|
13 |
O43173 (/IC)
Q92186 (/IC)
Q92186 (/IC)
Q92187 (/IC)
Q92187 (/IC)
Q92187 (/IC)
Q92187 (/IC)
Q92187 (/IC)
Q92187 (/IC)
Q92187 (/IC)
(3 more) |
|
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity GO:0003828
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
|
11 |
A7MCS5 (/ISS)
B0CN48 (/ISS)
F1R0F8 (/ISS)
Q4KMD8 (/ISS)
Q50J33 (/ISS)
Q50J35 (/ISS)
Q6KBZ7 (/ISS)
Q6KC03 (/ISS)
Q6KC05 (/ISS)
Q6ZXC9 (/ISS)
(1 more) |
|
Sialyltransferase activity GO:0008373
Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
|
10 | O43173 (/IDA) Q1LVN2 (/IDA) Q4KMD8 (/IDA) Q50J31 (/IDA) Q50J33 (/IDA) Q6KC03 (/IDA) Q7ZU51 (/IDA) Q8K4T1 (/IDA) Q8K4T1 (/IDA) Q8QH83 (/IDA) |
|
Sialyltransferase activity GO:0008373
Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
|
6 | P61644 (/ISS) P61647 (/ISS) Q1LVN2 (/ISS) Q50J31 (/ISS) Q7ZU51 (/ISS) Q8QH83 (/ISS) |
|
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity GO:0003828
Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
|
4 | O35696 (/ISO) Q64689 (/ISO) Q64692 (/ISO) Q64692 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O35696 (/IPI) Q64690 (/IPI) |
|
Sialyltransferase activity GO:0008373
Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
|
2 | A1KQY6 (/TAS) Q07977 (/TAS) |
|
Sialyltransferase activity GO:0008373
Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
|
1 | Q64689 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | O43173 (/IPI) |
Showing 1 to 10 of 11 entries
There are 33 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ganglioside biosynthetic process GO:0001574
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
15 |
O43173 (/IDA)
Q8K4T1 (/IDA)
Q8K4T1 (/IDA)
Q92186 (/IDA)
Q92186 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
(5 more) |
|
Oligosaccharide metabolic process GO:0009311
The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
|
15 |
O43173 (/IDA)
Q8K4T1 (/IDA)
Q8K4T1 (/IDA)
Q92186 (/IDA)
Q92186 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
(5 more) |
|
Protein glycosylation GO:0006486
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
|
13 |
O43173 (/IDA)
Q92186 (/IDA)
Q92186 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
(3 more) |
|
N-glycan processing GO:0006491
The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.
|
13 |
O43173 (/IDA)
Q92186 (/IDA)
Q92186 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
Q92187 (/IDA)
(3 more) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
12 |
Q92186 (/TAS)
Q92186 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
(2 more) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
12 |
Q92186 (/TAS)
Q92186 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
(2 more) |
|
Ganglioside biosynthetic process GO:0001574
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
|
4 | O35696 (/ISO) Q64689 (/ISO) Q64692 (/ISO) Q64692 (/ISO) |
|
Protein glycosylation GO:0006486
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
|
4 | O35696 (/ISO) Q64689 (/ISO) Q64692 (/ISO) Q64692 (/ISO) |
|
N-glycan processing GO:0006491
The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.
|
4 | O35696 (/ISO) Q64689 (/ISO) Q64692 (/ISO) Q64692 (/ISO) |
|
Oligosaccharide metabolic process GO:0009311
The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
|
4 | O35696 (/ISO) Q64689 (/ISO) Q64692 (/ISO) Q64692 (/ISO) |
Showing 1 to 10 of 33 entries
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
14 |
O43173 (/TAS)
P61647 (/TAS)
Q92186 (/TAS)
Q92186 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
Q92187 (/TAS)
(4 more) |
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
1 | O35696 (/IDA) |
|
Recycling endosome GO:0055037
An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
|
1 | O35696 (/IDA) |
Showing 1 to 3 of 3 entries
