View in Gene3D

CATH Superfamily 3.90.1170.20

Quinolinate phosphoribosyl transferase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Quinolinate phosphoribosyl transferase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3: Nicotinate-nucleotide pyrophosphorylase [carboxyla...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nicotinate-nucleotide diphosphorylase (carboxylating). [EC: 2.4.2.19]
Beta-nicotinate D-ribonucleotide + diphosphate + CO(2) = pyridine-2,3- dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate.
  • The reaction is catalyzed in the opposite direction.
  • Since quinolinate is synthesized from L-tryptophan in eukaryotes, but from L-aspartate in some prokaryotes, this is the first NAD(+) biosynthesis enzyme shared by both eukaryotes and prokaryotes.
 27 A7A287 A7A287 A7A287 A7A287 A7A287 A7SG73 C7GYF0 C7GYF0 C7GYF0 C7GYF0
(17 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...