The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Ribonuclease Inhibitor
".
FunFam 15: Leucine rich repeat containing 38
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
4 | Q2I0M4 (/IDA) Q5VT99 (/IDA) Q8N7C0 (/IDA) Q8N7C0 (/IDA) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
4 | Q2I0M4 (/IPI) Q5VT99 (/IPI) Q8N7C0 (/IPI) Q8N7C0 (/IPI) |
|
Potassium channel activator activity GO:0099104
Direct interaction with a potassium channel (binding or modification), resulting in its opening.
|
4 | Q2I0M4 (/IDA) Q5VT99 (/IDA) Q8N7C0 (/IDA) Q8N7C0 (/IDA) |
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
3 | A2VDH3 (/ISO) Q5M8M9 (/ISO) Q91W20 (/ISO) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
3 | A2VDH3 (/ISO) Q5M8M9 (/ISO) Q91W20 (/ISO) |
|
Potassium channel activator activity GO:0099104
Direct interaction with a potassium channel (binding or modification), resulting in its opening.
|
3 | A2VDH3 (/ISO) Q5M8M9 (/ISO) Q91W20 (/ISO) |
|
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
|
2 | Q6P7C4 (/ISS) Q91W20 (/ISS) |
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | Q5M8M9 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q2I0M4 (/IPI) |
|
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
|
1 | Q2I0M4 (/IDA) |
|
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
|
1 | Q91W20 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
4 | Q2I0M4 (/IDA) Q5VT99 (/IDA) Q8N7C0 (/IDA) Q8N7C0 (/IDA) |
|
Positive regulation of voltage-gated potassium channel activity GO:1903818
Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.
|
4 | Q2I0M4 (/IDA) Q5VT99 (/IDA) Q8N7C0 (/IDA) Q8N7C0 (/IDA) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
3 | A2VDH3 (/ISO) Q5M8M9 (/ISO) Q91W20 (/ISO) |
|
Positive regulation of voltage-gated potassium channel activity GO:1903818
Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.
|
3 | A2VDH3 (/ISO) Q5M8M9 (/ISO) Q91W20 (/ISO) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q5M8M9 (/IMP) |
|
Reproductive process GO:0022414
A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
|
1 | Q5M8M9 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
4 | Q2I0M4 (/IDA) Q5VT99 (/IDA) Q8N7C0 (/IDA) Q8N7C0 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q5VT99 (/ISS) Q8N7C0 (/ISS) Q8N7C0 (/ISS) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
3 | A2VDH3 (/ISO) Q5M8M9 (/ISO) Q91W20 (/ISO) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
2 | Q6P7C4 (/ISS) Q91W20 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q2I0M4 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q91W20 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q2I0M4 (/HDA) |
