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CATH Superfamily 3.60.20.10

Aminohydrolase, N-terminal nucleophile (Ntn) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
4
Proteasome subunit alpha type-4
1328
3D
 6hwfQ00 - 96.3
3
Proteasome subunit beta type-3
1230
3D
 6avoY00 - 96.1
5
Proteasome subunit beta type-2
1203
3D
 6hvwV00 - 94.2
8
Proteasome subunit beta type-4
1047
3D
 6avoV00 - 95.9
10
Proteasome subunit beta type-1
1019
3D
 6avoF00 - 94.0
14
Proteasome subunit beta type-7
912
3D
 6hwfa00 - 92.5
9
Proteasome subunit alpha type-3
898
3D
 6hwfP00 - 70.2
15
Proteasome subunit alpha type-5
897
3D
 6hwfR00 - 79.1
16
Proteasome subunit alpha type-6
868
3D
 6hwfS00 - 92.4
13
Proteasome subunit beta type-5
849
3D
 6hwfY00 - 78.0
26
Proteasome subunit alpha type-1
781
3D
 6hwfU00 - 86.5
27
Proteasome subunit beta type-6
771
3D
 5m2bZ00 - 93.4
2
ATP-dependent protease subunit HslV
731
3D
 5ji3D00 - 78.8
1
Glutamate synthase, large subunit
726
3D
 1ofeB01 - 92.3
44
Probable proteasome subunit alpha type-7
671
3D
 6hwfT00 - 72.2
48
Proteasome subunit alpha type-2
649
3D
 6hwfO00 - 71.6
6
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
600
3D
 4amvC01 - 93.1
7
Proteasome subunit alpha type
457
3D
 5a0qU00 - 93.6
11
Amidophosphoribosyltransferase
411
3D
 6czfD01 - 69.0
12
Proteasome subunit alpha type
401
3D
 6avob00 - 90.4
23
Proteasome subunit alpha
361
3D
 6bglO00 - 67.9
18
Proteasome subunit alpha type
337
3D
 6avoN00 - 78.4
19
Proteasome subunit alpha type
328
3D
 6avoM00 - 85.8
20
Proteasome subunit alpha type
314
3D
 6avoR00 - 83.6
17
Glucosamine-fructose-6-phosphate aminotransferase, isomerising
292 - - 74.2
22
Proteasome subunit alpha type
279
3D
 6avoZ00 - 74.6
21
glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
264 - - 78.7
25
Proteasome subunit alpha type
260
3D
 6avoL00 - 78.8
24
Asparagine synthetase [glutamine-hydrolyzing]
216 - - 71.8
30
Proteasome subunit beta
211
3D
 5vfor00 - 72.5
49
Proteasome subunit beta
204
3D
 6bdfZ00 - 95.4
33
Proteasome subunit beta
200
3D
 6avoX00 - 87.2
38
Proteasome subunit beta
194
3D
 5m2bY00 - 72.0
28
Proteasome subunit alpha type
174 - - 71.7
29
Proteasome subunit alpha type
170 - - 71.5
31
Proteasome subunit alpha type
167 - - 85.0
32
Proteasome subunit beta
160 - - 72.1
34
Proteasome subunit beta
152
3D
 6qm8Z00 - 73.7
35
Proteasome subunit beta
145 - - 58.5
36
Proteasome subunit alpha type
143 - - 76.9
37
Asparagine synthetase B
143
3D
 1ct9D01 - 62.0
39
Asparagine synthetase [glutamine-hydrolyzing]
135 - - 85.5
40
Proteasome subunit beta
131 - - 63.0
41
Asparagine synthase
Glutamine-hydrolyzing
130 - - 10.9
46
Proteasome subunit beta
130
3D
 3mkaZ00 - 71.2
42
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
119 - - 85.4
43
Glutamate synthase 1 [NADH] chloroplastic
112 - - 81.5
45
Glutamine amidotransferase DUG3
102 - - 78.5
47
Amidophosphoribosyltransferase
85 - - 67.9
50
Asparagine synthetase 2
67 - - 75.7
77
Proteasome subunit alpha type-3
67
3D
 6avoQ00 - 14.7
51
Proteasome subunit beta
66
3D
 5fmgZ00 - 81.4
52
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
56 - - 84.9
55
Proteasome subunit alpha type
50
3D
 6qm8O00 - 96.3
54
Proteasome subunit alpha type
50
3D
 5fmgS00 - 83.2
53
Proteasome subunit beta
48 - - 73.4
56
NAD
P
44 - - 19.3
80
Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase
42
3D
 4zflL00 - 57.0
57
ATP-dependent protease subunit ClpQ, putative
35 - - 8.0
58
Proteasome subunit alpha type
35
3D
 5fmgQ00 - 71.8
61
Heat stress transcription factor A-6b
28 - - 73.9
59
Proteasome subunit alpha type
28 - - 49.7
60
Related to DUG3-probable glutamine amidotransferase
28 - - 80.1
62
Proteasome subunit alpha type
27 - - 35.0
63
Proteasome subunit alpha type
27 - - 89.6
64
Proteasome subunit beta type-6
26
3D
 5fmgV00 - 87.0
65
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
22 - - 7.4
74
Proteasome subunit beta
21
3D
 6qm8b00 - 92.0
66
Proteasome subunit alpha type
21 - - 23.9
67
Glutamine-fructose-6-phosphate transaminase
Isomerizing
19 - - 3.7
68
NAD
P
19 - - 4.1
186
Acyl-homoserine lactone acylase PvdQ
18
3D
 4wkvC01 - 1.3
70
Proteasome subunit beta
18 - - 81.9
69
Proteasome subunit beta 12
18 - - 41.7
76
Proteasome subunit beta
17
3D
 5fmga00 - 5.1
72
Proteasome subunit alpha type
17 - - 73.4
71
Proteasome subunit beta
17 - - 4.6
73
Proteasome subunit beta
17 - - 62.7
81
Proteasome subunit beta
16
3D
 5fmgY00 - 10.8
75
Asparagine synthase
Glutamine-hydrolyzing
16 - - 1.2
78
Amidophosphoribosyltransferase
15 - - 14.5
82
Glutamate synthase, large subunit
14 - - 48.6
79
Proteasome subunit beta 2
14 - - 35.9
89
Proteasome endopeptidase complex
14
3D
 5fmgO00 - 2.6
87
Asparagine synthase B
13 - - 6.7
105
Proteasome subunit beta
13
3D
 6qm8a00 - 25.9
85
Proteasome subunit beta
13 - - 14.9
83
Proteasome subunit beta
13 - - 77.2
84
Class II glutamine amidotransferase
13 - - 75.9
93
Proteasome endopeptidase complex
13
3D
 5fmgT00 - 7.9
86
Proteasome subunit beta type-1
13 - - 16.2
88
Proteasome subunit beta
12 - - 17.3
96
Ferredoxin-dependent glutamate synthase, chloroplastic
11 - - 10.6
94
Proteasome subunit beta
11 - - 13.3
90
Proteasome subunit beta
11 - - 26.1
91
Proteasome subunit beta
11 - - 37.6
95
Asparagine synthase
Glutamine-hydrolyzing
11 - - 12.1
92
Class II glutamine amidotransferase
11 - - 9.5
97
Proteasome subunit alpha type
11 - - 32.2
98
Proteasome subunit beta
10 - - 25.4
99
Proteasome subunit beta
10 - - 24.2
100
Proteasome subunit beta
10 - - 27.2
102
Asparagine synthetase
10 - - 35.7
104
YML096W-like protein
10 - - 4.8
103
ASparagiNe Synthetase
10 - - 66.2
101
Proteasome subunit alpha type
10 - - 15.1
106
Asparagine synthetase
9 - - 50.4
107
Probable proteasome subunit beta type-5
9 - - 46.7
109
Asparagine synthetase B
8 - - 0.0
108
Proteasome subunit beta
8 - - 42.9
113
Asparagine synthase
Glutamine-hydrolysing
7 - - 20.8
111
Proteasome subunit beta
7 - - 5.1
112
Proteasome subunit beta
7 - - 0.0
114
Asparagine synthetase, glutamine-hydrolyzing
7 - - 11.0
116
Proteasome endopeptidase complex
7 - - 44.8
110
Proteasome subunit beta type-6, putative
7 - - 5.9
115
Probable asparagine synthase
7 - - 16.3
121
Proteasome subunit beta
6 - - 7.5
123
Proteasome subunit beta
6 - - 1.2
117
Proteasome endopeptidase complex
6 - - 7.3
118
Proteasome endopeptidase complex
6 - - 8.5
122
Proteasome subunit beta type-1, putative
6 - - 2.7
124
Proteasome endopeptidase complex
6 - - 40.1
120
Proteasome subunit beta type 7-B, putative
6 - - 0.0
119
20S proteasome alpha subunit 7
6 - - 13.1
133
SIS domain containing protein
5 - - 70.4
131
Proteasome subunit beta
5 - - 8.4
128
Proteasome subunit beta
5 - - 4.2
127
Glutamine amidotransferase
5 - - 12.9
134
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
5 - - 9.7
132
Asparagine synthase
5 - - 10.0
126
Proteasome subunit alpha type
5 - - 5.8
130
Proteasome subunit beta type 9
5 - - 7.8
135
Acyl-homoserine lactone acylase QuiP
5 - - 0.0
125
Proteasome subunit alpha type
5 - - 3.5
129
Proteasome subunit beta
5 - - 7.0
145
Proteasome subunit alpha type
4 - - 47.6
137
Proteasome subunit alpha type
4 - - 20.3
138
Proteasome subunit alpha type
4 - - 1.0
140
Proteasome endopeptidase complex
4 - - 9.1
136
Proteasome subunit beta
4 - - 14.9
142
Glucosamine-fructose-6-phosphate aminotransferase, putative
4 - - 12.3
144
Glutamine-fructose-6-phosphate transaminase
Isomerizing GlmS-2
4 - - 1.4
143
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing
4 - - 5.7
141
Asparagine synthetase, putative
4 - - 36.9
139
Proteasome subunit beta
4 - - 9.1
151
Proteasome endopeptidase complex
3 - - 3.9
153
3 - - 2.3
149
Proteasome subunit beta
3 - - 6.1
146
3 - - 14.8
152
3 - - 0.9
154
Acyl-homoserine lactone acylase QuiP
3 - - 0.4
147
3 - - 31.6
150
Proteasome endopeptidase complex
3 - - 5.0
148
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing]
3 - - 2.6
155
Asparagine synthetase
Eurofung
3 - - 32.9
166
2 - - 7.9
185
2 - - 0.0
160
2 - - 43.5
177
2 - - 8.9
178
2 - - 9.0
189
2 - - 39.2
172
2 - - 2.3
174
2 - - 0.6
173
2 - - 0.0
180
2 - - 2.5
171
2 - - 1.0
158
2 - - 38.4
157
2 - - 10.8
165
2 - - 0.0
190
2 - - 40.8
169
2 - - 0.0
156
2 - - 12.1
188
2 - - 30.8
161
2 - - 0.0
163
2 - - 0.0
187
2 - - 36.8
175
2 - - 2.4
184
2 - - 0.0
179
2 - - 9.4
182
2 - - 31.1
176
2 - - 7.9
181
2 - - 11.2
168
2 - - 7.7
183
2 - - 6.2
167
2 - - 0.0
170
2 - - 4.6
162
2 - - 0.0
164
2 - - 0.0
159
2 - - 44.0
217
1 - - 0.0
258
1 - - 0.0
228
1 - - 0.0
218
1 - - 0.0
240
1 - - 0.0
257
1 - - 0.0
227
1 - - 0.0
265
1 - - 0.0
199
1 - - 0.0
237
1 - - 0.0
271
1 - - 0.0
238
1 - - 0.0
246
1 - - 0.0
214
1 - - 0.0
269
1 - - 0.0
232
1 - - 0.0
195
1 - - 0.0
200
1 - - 0.0
224
1 - - 0.0
254
1 - - 0.0
234
1 - - 0.0
252
1 - - 0.0
222
1 - - 0.0
212
1 - - 0.0
206
1 - - 0.0
209
1 - - 0.0
260
1 - - 0.0
233
1 - - 0.0
245
1 - - 0.0
231
1 - - 0.0
221
1 - - 0.0
251
1 - - 0.0
213
1 - - 0.0
266
1 - - 0.0
223
1 - - 0.0
253
1 - - 0.0
211
1 - - 0.0
249
1 - - 0.0
205
1 - - 0.0
196
1 - - 0.0
268
1 - - 0.0
215
1 - - 0.0
225
1 - - 0.0
255
1 - - 0.0
267
1 - - 0.0
194
1 - - 0.0
270
1 - - 0.0
235
1 - - 0.0
192
1 - - 0.0
243
1 - - 0.0
241
1 - - 0.0
219
1 - - 0.0
198
1 - - 0.0
264
1 - - 0.0
197
1 - - 0.0
259
1 - - 0.0
229
1 - - 0.0
239
1 - - 0.0
262
1 - - 0.0
203
1 - - 0.0
201
1 - - 0.0
247
1 - - 0.0
204
1 - - 0.0
250
1 - - 0.0
220
1 - - 0.0
248
1 - - 0.0
210
1 - - 0.0
236
1 - - 0.0
226
1 - - 0.0
256
1 - - 0.0
261
1 - - 0.0
230
1 - - 0.0
202
1 - - 0.0
263
1 - - 0.0
216
1 - - 0.0
207
1 - - 0.0
244
1 - - 0.0
208
1 - - 0.0
191
1 - - 0.0
242
1 - - 0.0
193
1 - - 0.0
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