The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Janus/Ocnus
".
FunFam 1: 14 kDa phosphohistidine phosphatase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein histidine phosphatase activity GO:0101006
Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate
|
4 | D3ZP47 (/IDA) P59083 (/IDA) Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9NRX4 (/IPI) Q9NRX4 (/IPI) |
|
Calcium channel inhibitor activity GO:0019855
Stops, prevents, or reduces the activity of a calcium channel.
|
2 | Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | Q9NRX4 (/IPI) Q9NRX4 (/IPI) |
|
Protein histidine phosphatase activity GO:0101006
Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate
|
2 | Q9NRX4 (/IMP) Q9NRX4 (/IMP) |
|
Calcium channel inhibitor activity GO:0019855
Stops, prevents, or reduces the activity of a calcium channel.
|
1 | Q9DAK9 (/ISO) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
1 | Q9DAK9 (/ISO) |
|
Protein histidine phosphatase activity GO:0101006
Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate
|
1 | Q9DAK9 (/ISO) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
|
10 | P54364 (/ISS) P54364 (/ISS) P83752 (/ISS) P83752 (/ISS) P83753 (/ISS) P83753 (/ISS) Q9BM96 (/ISS) Q9BM97 (/ISS) Q9BM98 (/ISS) Q9BM99 (/ISS) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | D3ZP47 (/IDA) Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Peptidyl-histidine dephosphorylation GO:0035971
The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.
|
3 | P59083 (/IDA) Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Negative regulation of lyase activity GO:0051350
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
|
3 | D3ZP47 (/IDA) Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
3 | Q9DAK9 (/IMP) Q9NRX4 (/IMP) Q9NRX4 (/IMP) |
|
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
|
2 | Q9NRX4 (/IMP) Q9NRX4 (/IMP) |
|
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
|
2 | Q9NRX4 (/IMP) Q9NRX4 (/IMP) |
|
Negative regulation of ATP citrate synthase activity GO:2000984
Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.
|
2 | Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q9DAK9 (/ISO) |
|
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
|
1 | P20348 (/IEP) |
|
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
1 | D3ZP47 (/IMP) |
|
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
|
1 | Q9DAK9 (/ISO) |
|
Peptidyl-histidine dephosphorylation GO:0035971
The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.
|
1 | Q9DAK9 (/ISO) |
|
Negative regulation of T cell receptor signaling pathway GO:0050860
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
|
1 | Q9DAK9 (/ISO) |
|
Negative regulation of lyase activity GO:0051350
Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
|
1 | Q9DAK9 (/ISO) |
|
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
1 | Q9DAK9 (/ISO) |
|
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
|
1 | Q9DAK9 (/ISO) |
|
Negative regulation of ATP citrate synthase activity GO:2000984
Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.
|
1 | Q9DAK9 (/ISO) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | D3ZP47 (/IDA) P59083 (/IDA) Q9DAK9 (/IDA) Q9NRX4 (/IDA) Q9NRX4 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | Q9NRX4 (/HDA) Q9NRX4 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9DAK9 (/ISO) |
