The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Kinesin motor domain
".
FunFam 65: Kinesin-like protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ATP-dependent microtubule motor activity, minus-end-directed GO:0008569
Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP.
|
2 | P28739 (/IDA) Q9US03 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9US03 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | Q9US03 (/ISM) |
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | Q9US03 (/IDA) |
|
ATP-dependent microtubule motor activity, minus-end-directed GO:0008569
Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP.
|
1 | Q9US03 (/IMP) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
|
1 | Q9US03 (/IMP) |
|
Karyogamy involved in conjugation with cellular fusion GO:0000742
During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.
|
1 | Q9US03 (/IGI) |
|
Microtubule bundle formation GO:0001578
A process that results in a parallel arrangement of microtubules.
|
1 | Q9US03 (/IDA) |
|
Establishment or maintenance of microtubule cytoskeleton polarity GO:0030951
Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.
|
1 | Q9US03 (/IMP) |
|
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
|
1 | Q9US03 (/IMP) |
|
Minus-end directed microtubule sliding GO:0031534
The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.
|
1 | Q9US03 (/IMP) |
|
Microtubule sliding GO:0051012
The movement of one microtubule along another microtubule.
|
1 | Q9US03 (/IMP) |
|
Mitotic spindle assembly GO:0090307
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.
|
1 | P28739 (/IMP) |
|
Nuclear migration during mitotic telophase GO:0090561
The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.
|
1 | Q9US03 (/IGI) |
|
Microtubule sliding involved in mitotic metaphase chromosome recapture GO:1905185
Any microtubule sliding that is involved in mitotic metaphase chromosome recapture.
|
1 | Q9US03 (/IMP) |
|
Microtubule anchoring at mitotic spindle pole body GO:1990810
Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
|
1 | Q9US03 (/IGI) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Astral microtubule GO:0000235
Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
|
1 | Q9US03 (/IDA) |
|
Condensed nuclear chromosome kinetochore GO:0000778
A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules.
|
1 | Q9US03 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9US03 (/IDA) |
|
Minus-end kinesin complex GO:0005872
Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule.
|
1 | Q9US03 (/IDA) |
|
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
1 | Q9US03 (/HDA) |
|
Microtubule plus-end GO:0035371
The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.
|
1 | Q9US03 (/IDA) |
|
Microtubule minus-end GO:0036449
The end of a microtubule that does not preferentially grow (polymerize).
|
1 | Q9US03 (/IDA) |
|
Cortical microtubule GO:0055028
Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.
|
1 | Q9US03 (/IDA) |
|
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | Q9US03 (/IDA) |
