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CATH Superfamily 3.40.50.970

Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Glyoxylate carboligasePyruvate dehydrogenase [ubiquinone]2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseOxalyl-CoA decarboxylase2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseN(2)-(2-carboxyethyl)arginine synthaseSC:22-oxoisovalerate dehydrogenase subunit alphaPyruvate dehydrogenase E1 component subunit alphaSC:32-oxoglutarate dehydrogenase E1 component2-oxoglutarate dehydrogenase E1 componentPyruvate dehydrogenase E1 component subunit alpha, mitochondrialSC:4Pyruvate dehydrogenase E1 component subunit beta1-deoxy-D-xylulose-5-phosphate synthase1-deoxy-D-xylulose-5-phosphate synthasePyruvate:ferredoxin (Flavodoxin) oxidoreductase2-oxoglutarate ferredoxin oxidoreductase alpha subunitUbiquinone-dependent pyruvate dehydrogenaseTransketolase isoform 12-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseOxalyl-CoA decarboxylaseTransketolase2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseSC:5Pyruvate:ferredoxin (Flavodoxin) oxidoreductaseSC:6Transketolase isoform 1TransketolasePyruvate dehydrogenase E1 beta subunit2-oxoglutarate dehydrogenase, E1 componentTransketolaseTransketolase1-deoxy-D-xylulose-5-phosphate synthaseAcetolactate synthasePyruvate dehydrogenase E1 componentPyruvate dehydrogenase E1 componentPyruvate dehydrogenase E1 component subunit alphaAcetolactate synthasepyruvate decarboxylase 1Pyruvate decarboxylase isozymePyruvate decarboxylase 1Pyruvate decarboxylase isozyme2-hydroxyacyl-CoA lyase 11-deoxy-D-xylulose-5-phosphate synthase2-oxoisovalerate dehydrogenase subunit alphaProbable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial2-oxoglutarate dehydrogenase E1 component2-oxoacid:ferredoxin oxidoreductase subunit beta2-hydroxyacyl-CoA lyase 1 isoform X1Indolepyruvate oxidoreductase subunit IorAIlvB acetolactate synthase likePutative acetolactate synthase IlvG2-hydroxyacyl-CoA lyase 1Probable pyruvate-flavodoxin oxidoreductaseIlvB (bacterial acetolactate synthase)-like2-oxoglutarate ferredoxin oxidoreductase subunit beta2-hydroxyacyl-CoA lyaseSulfite reductase beta subunitSulfite reductase [NADPH] flavoprotein componentAcetolactate synthase, mitochondrialPutative 2-hydroxyphytanoyl-CoA lyase2-oxoisovalerate dehydrogenase subunit alpha3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase2-oxoisovalerate dehydrogenase subunit alphaPutative pyruvate decarboxylase2-oxoisovalerate dehydrogenase E1 component1-deoxy-D-xylulose-5-phosphate synthase2-oxoglutarate dehydrogenase E1 componentAcetolactate synthase, catabolic2-oxoglutarate dehydrogenase, mitochondrial1-deoxy-D-xylulose 5-phosphate synthaseOxoglutarate dehydrogenase (Succinyl-transferring), E1 component2-hydroxyacyl-CoA lyase 11-deoxy-D-xylulose 5-phosphate synthase2-oxoglutarate dehydrogenase E1 component2-hydroxyphytanoyl-CoA lyase, putative3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase2-oxoisovalerate dehydrogenase subunit alpha2-oxoglutarate dehydrogenase E1 componentOxoglutarate dehydrogenase (Succinyl-transferring), E1 componentTransketolasePyruvate dehydrogenase E1 component subunit betaSulfite reductase (NADPH) hemoprotein, beta-componentIndolepyruvate ferredoxin oxidoreductase alpha subunitIndolepyruvate oxidoreductase subunit IorAOxoglutarate dehydrogenaseSulfite reductase (NADPH) hemoprotein, beta-componentProbable 2-ketoarginine decarboxylase AruISulfite reductase [NADPH] subunit betaSulfite reductase (NADPH) hemoprotein, beta-componentThi3pPutative acetolactate synthase IlvGPutative indole-3-pyruvate decarboxylaseSulfoacetaldehyde acetyltransferaseXylulose-5-phosphate/fructose-6-phosphate phosphoketolase2-oxoglutarate decarboxylase/hydro-lyase/magnesium ion-binding protein1-deoxy-D-xylulose-5-phosphate synthase2-oxoisovalerate dehydrogenase E1 componentSulfopyruvate decarboxylase subunit betaPyruvate dehydrogenase E1 alpha 1 subunitMet5 proteinSulfite reductase alpha subunitProbable acetohydroxyacid synthase ilvXPutative phosphonopyruvate decarboxylasePutative phosphonopyruvate decarboxylaseProtein PHYLLO, chloroplastic2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase1-deoxy-D-xylulose-5-phosphate synthase2-oxoglutarate dehydrogenase E1 component, putativePyruvate:ferredoxin (Flavodoxin) oxidoreductaseSulfoacetaldehyde acetyltransferase Xsc2-oxoisovalerate dehydrogenase subunit alphaIndolepyruvate oxidoreductase subunit IorAPyruvate-flavodoxin oxidoreductaseUncharacterized proteinDehydrogenase E1 componentOxalate oxidoreductase subunit betaIndolepyruvate ferredoxin oxidoreductase alpha subunitProbable acetohydroxyacid synthase ilvXIndolepyruvate oxidoreductase subunit IorATransketolaseIndolepyruvate oxidoreductase subunit IorA2-oxoglutarate dehydrogenase, putativePyruvate dehydrogenase (Ferredoxin/flavodoxin-dependent)Sulfite reductase beta subunitRelated to MET10-sulfite reductase flavin-binding subunitPutative acetolactate synthase large subunit1-deoxy-D-xylulose-5-phosphate synthase2-oxoacid:ferredoxin oxidoreductase, beta subunitPhosphonopyruvate decarboxylase-like proteinPhosphonopyruvate decarboxylase-like proteinPutative 2-oxoglutarate dehydrogenase subunitTransketolase2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit1-deoxy-D-xylulose-5-phosphate synthasePyruvate dehydrogenase E1 component subunit alphaUncharacterized proteinPutative inositol polyphosphate phosphatase (Synaptogenin-like) family proteinSulfite reductase [NADPH] flavoprotein component, putativeNADH-dependent phenylglyoxylate dehydrogenase subunit betaPyruvate oxidasePyruvate oxidaseAcetolactate synthase-1/2/3 large subunitPhenylpyruvate decarboxylase1-deoxy-D-xylulose-5-phosphate synthase1-deoxy-D-xylulose-5-phosphate synthaseUncharacterized protein2-hydroxyacyl-CoA lyasePyruvate dehydrogenase E1 component subunit betaPyruvate dehydrogenase E1 component subunit betaPyruvate-flavodoxin oxidoreductasePyruvate dehydrogenase E1 component beta subunit2-oxoisovalerate dehydrogenase subunit alphaIndolepyruvate oxidoreductase subunit IorAIndolepyruvate oxidoreductase subunit IorAPredicted protein2-oxoglutarate dehydrogenase, putativeUncharacterized proteinPredicted proteinUncharacterized proteinOxoglutarate dehydrogenaseSulfite reductase (NADPH) subunit betaProbable 2-hydroxyacyl-CoA lyase 1Benzaldehyde lyase, putativeTransketolase putativeThiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha2-oxoglutarate:ferredoxin oxidoreductase, thiamin diphosphate-binding subunitPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialUncharacterized proteinTransketolase chloroplast putativePyruvate dehydrogenase E1 component beta subunitAlpha-ketoacid dehydrogenase subunit beta2-oxoisovalerate dehydrogenase subunit alpha2-oxoisovalerate dehydrogenase subunit alphaUncharacterized proteinPredicted proteinUncharacterized proteinPyruvate dehydrogenase E1 component alpha subunit, putativePyruvate dehydrogenase E1 component alpha subunit, putativeIndolepyruvate oxidoreductase subunit IorAProbable 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrialOxoglutarate dehydrogenase (Succinyl-transferring), E1 component2-oxoglutarate dehydrogenase, mitochondrial2-oxoglutarate dehydrogenase, E1 proteinTransketolase-1 chloroplasticUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinPyruvate:ferredoxin oxidoreductase FUncharacterized proteinUncharacterized proteinSulfite reductase [NADPH] subunit betaPredicted proteinUncharacterized proteinThiamine diphosphate dependent-3-acetyloctanal synthase PigDPyruvate decarboxylase 2Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrialPyruvate decarboxylaseUncharacterized protein2-hydroxyphytanoyl-CoA lyase, putativeAcetolactate synthase, catabolic, putativeProbable 2-ketoarginine decarboxylase AruIUncharacterized proteinUncharacterized proteinPyruvate dehydrogenase E1 component subunit beta, mitochondrialPyruvate dehydrogenase E1 component subunit beta, mitochondrialPredicted proteinPyruvate ferredoxin oxidoreductase BPutative 2-dehydropantoate 2-reductaseUncharacterized proteinUncharacterized protein2-oxoisovalerate dehydrogenase subunit alphaPyruvate dehydrogenase E1 alpha 1 subunit bUncharacterized proteinProtein CBG00293Uncharacterized proteinPyruvate decarboxylase 2Uncharacterized proteinUncharacterized proteinUncharacterized protein, isoform F2-oxoisovalerate dehydrogenase subunit alphaUncharacterized protein2-hydroxyacyl-CoA lyase 1Uncharacterized proteinPyruvate dehydrogenase E1 alpha 1 subunit2-oxoisovalerate dehydrogenase subunit alphaGll1094 proteinPredicted proteinGll1094 proteinTransketolase, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinPutative 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial-like Protein2-oxoglutarate dehydrogenase E1 componentOxoglutarate dehydrogenase
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FunFam 167: Uncharacterized protein

Representative CATH Domain Q1K672/1-55

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Sequence alignment 200 sequences

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