CATH Superfamily 3.40.50.80

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	NADPH--cytochrome P450 reductase 1	651	3D	3fjoA05	-	94.8
2	Ferredoxin--NADP reductase	490	3D	3crzA02	-	81.5
3	Nitric oxide synthase	420	3D	1tllB04	-	85.8
4	NADPH oxidase isoform 2	410	3D	3a1fA00	-	88.9
5	NADH-cytochrome b5 reductase	359	3D	1umkA02	-	91.3
8	Ferredoxin--NADP reductase, chloroplastic	329	3D	4c43A02	-	94.5
6	Dual oxidase 2	259		-	-	71.5
7	Respiratory burst oxidase protein A	246		-	-	86.2
10	Flavohemoprotein	243	3D	1gvhA03	-	98.1
9	NADH-cytochrome b5 reductase	232		-	-	94.0
11	Sulfite reductase flavoprotein component	191		-	-	73.1
13	Ferredoxin--NADP +	176	3D	2xnjB02	-	73.2
14	Na +	176	3D	4u9uB02	-	83.2
12	NADPH oxidase, isoform B	172		-	-	86.1
15	NADPH oxidase 4	157		-	-	76.6
16	NAD P	151	3D	1qfjD02	-	44.6
17	Dihydroorotate dehydrogenase B NAD(+	144		-	-	77.3
18	NADPH--cytochrome P450 reductase	133	3D	2qtzA03	-	92.3
19	NADH-cytochrome b5 reductase	113	3D	2eixB02	-	86.9
20	Dual oxidase 1	111		-	-	79.8
21	Cytochrome b5 reductase 4	107		-	-	95.3
22	Siderophore-interacting family protein	105		-	-	68.4
23	Putative ferric-chelate reductase	93		-	-	76.6
24	NADH oxidoreductase hcr	87		-	-	2.9
25	Nitrate reductase [NADH]	85	3D	2cndA02	-	88.9
26	Putative respiratory burst oxidase	77		-	-	55.8
27	FAD binding domain protein	74		-	-	71.1
28	Respiratory burst oxidase protein E	71		-	-	59.3
29	NADPH oxidase A	61		-	-	69.8
30	NADPH-dependent diflavin oxidoreductase 1	61		-	-	95.6
31	Bifunctional cytochrome P450/NADPH--P450 reductase	59	3D	4dqlB03	-	88.6
32	NADPH-dependent diflavin oxidoreductase 1	44		-	-	96.2
33	Sulfite reductase NADPH	43		-	-	73.4
34	Respiratory burst oxidase homolog protein B	43		-	-	27.9
51	Ferredoxin--NADP reductase, apicoplast	40	3D	3jqrA02	-	6.4
35	FRE4p Ferric reductase	38		-	-	93.8
36	Ferric reduction oxidase 6	36		-	-	85.2
37	Metalloreductase, putative	34		-	-	56.6
38	Vibriobactin utilization protein ViuB	33		-	-	87.8
39	Ferric reduction oxidase 3	31		-	-	87.8
40	Respiratory burst oxidase protein D	30		-	-	77.3
41	1,2-phenylacetyl-CoA epoxidase subunit E	28		-	-	68.5
42	Putative NADH-cytochrome b5 reductase	24		-	-	91.0
43	NADH-cytochrome b5 reductase	24		-	-	35.4
45	NADPH-cytochrome p450 reductase	21		-	-	90.3
44	Ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE	21		-	-	82.8
46	Probable ferric reductase transmembrane component	20		-	-	86.2
47	Naphthalene 1,2-dioxygenase reductase component	20		-	-	37.7
48	Ferric reduction oxidase 5	20		-	-	72.0
49	Nitrate reductase	19		-	-	74.1
50	Ferric reduction oxidase 6	18		-	-	83.3
52	NADH-cytochrome b5 reductase	17		-	-	54.5
63	Ferredoxin--NADP reductase	16	3D	5ufaC02	-	4.5
53	NADH-cytochrome b5 reductase	16		-	-	72.9
54	Ferric reduction oxidase 7	16		-	-	72.4
55	NADPH-dependent diflavin oxidoreductase 1	15		-	-	67.8
56	Probable ferredoxin	14		-	-	7.9
57	FAD-binding domain-domain-containing protein	14		-	-	73.0
59	Ferric reduction oxidase 4	13		-	-	14.9
58	Ferric reductase transmembrane component 4, variant	13		-	-	16.9
61	Metalloreductase transmembrane component, putative	12		-	-	93.7
60	Cupric reductase	12		-	-	92.1
64	Flavohemoprotein	11		-	-	39.2
62	NADPH-dependent diflavin oxidoreductase 1	11		-	-	15.2
66	Vanillate O-demethylase oxidoreductase	11		-	-	83.2
65	Nitric oxide dioxygenase	11		-	-	7.0
67	WGS project CABT00000000 data, contig 2.6	11		-	-	57.2
70	NADH-cytochrome b5 reductase	10		-	-	43.0
71	Cell surface metalloreductase FreA	10		-	-	86.8
68	Iron ABC transporter ATP-binding protein/permease IrtA	10		-	-	10.6
73	ferric reduction oxidase 8, mitochondrial	10		-	-	78.3
69	POSSIBLE OXYGENASE	10		-	-	10.4
74	Plasma membrane ferric-chelate reductase Fre2	10		-	-	85.3
72	Ferric reductase	10		-	-	2.7
75	BnaA08g31310D protein	9		-	-	15.2
76	Flavohemoprotein	9		-	-	79.3
79	Fre7p	8		-	-	4.9
78	NAD P	8		-	-	64.4
82	Metalloreductase, putative	8		-	-	78.2
81	Probable metalloreductase AIM14	8		-	-	5.6
77	Putative nitrate reductase	8		-	-	17.5
80	NADPH oxidoreductase	8		-	-	1.9
83	Ferric reduction oxidase 2	8		-	-	49.4
85	Iron-uptake factor	7		-	-	89.9
93	Putative cytochrome P450 reductase	7		-	-	83.8
87	Oxidoreductase	7		-	-	0.0
90	Methionine synthase reductase	7		-	-	84.8
86	NADPH-dependent ferric siderophore reductase	7		-	-	12.7
91	NADPH oxidase 4	7		-	-	84.3
88	Ferric-chelate reductase, putative	7		-	-	33.3
92	Similar to gi\|11359636\|pir\|\|T49761 related to ferric reductase	7		-	-	40.9
89	Uncharacterized protein	7		-	-	1.6
84	Oxidoreductase-like protein	7		-	-	44.6
94	Bifunctional cytochrome P450/NADPH--P450 reductase	6		-	-	15.6
98	Respiratory burst oxidase-like protein F isoform A	6		-	-	5.4
96	NADPH-dependent ferric siderophore reductase	6		-	-	21.3
97	Unplaced genomic scaffold supercont1.3, whole genome shotgun sequence	6		-	-	14.8
95	Uncharacterized protein	6		-	-	78.5
109	Ferredoxin reductase component of carbazole	5		-	-	0.0
99	NADPH-cytochrome P450 reductase	5		-	-	0.8
110	Respiratory burst oxidase	5		-	-	67.3
102	Putative reductase	5		-	-	0.0
107	AGAP003772-PA	5		-	-	13.5
100	Ferric reduction oxidase 2	5		-	-	11.4
106	Ferric reductase transmembrane component	5		-	-	47.8
101	Metalloreductase, putative	5		-	-	19.8
105	Ferric-chelate reductase, putative	5		-	-	71.4
103	Ferredoxin--NADP reductase	5		-	-	16.2
108	Terephthalate 1,2-dioxygenase, reductase component 2	5		-	-	8.6
104	BauF	5		-	-	1.5
123	Related to ferric reductase	4		-	-	13.0
119	Ferric reductase transmembrane component, putative	4		-	-	9.0
124	Ferric-chelate reductase	4		-	-	10.3
116	Uncharacterized protein	4		-	-	86.9
125	Flavohemoglobin	4		-	-	3.7
111	Respiratory burst oxidase	4		-	-	13.1
112	Putative nitrate reductase	4		-	-	7.9
117	Ferric reductase like transmembrane component-domain-containing protein	4		-	-	76.2
126	Probable oxidoreductase	4		-	-	0.0
120	Ferric reductase	4		-	-	10.9
115	Ferric reductase transmembrane component, putative	4		-	-	9.4
121	Uncharacterized protein	4		-	-	4.2
122	Repressed by TUP1 protein 2	4		-	-	9.3
127	Uncharacterized protein	4		-	-	73.4
118	Ferric-chelate reductase, putative	4		-	-	0.6
113	NADPH-dependent FMN/FAD containing oxidoreductase	4		-	-	3.7
114	Iron utilization protein	4		-	-	0.0
140	Ferric reductase like transmembrane component	3		-	-	32.2
128	Protein CBG08008	3		-	-	32.1
132	Nitric oxide synthase	3		-	-	9.8
137	Probable metalloreductase AIM14	3		-	-	0.7
141	Ferric reduction oxidase 8, mitochondrial isoform A	3		-	-	0.0
136	Ferric reductase transmembrane component, putative	3		-	-	4.3
142	Ferric reductase-like protein	3		-	-	62.8
130	Rieske_[2Fe-2S]_domain/Rieske-like_[2Fe-2S ]_domain_containing_protein_-_putative	3		-	-	8.1
131	Mitochondrial NADH-dependent fumarate reductase	3		-	-	0.9
139	Flavodoxin family protein	3		-	-	7.1
143	Cytochrome p450 oxidoreductase	3		-	-	63.1
144	Predicted protein	3		-	-	80.1
133	Methionine synthase reductase, mitochondrial-like protein	3		-	-	7.6
138	Metalloreductase Fre8	3		-	-	2.0
134	Ferric reductase like transmembrane component-domain-containing protein	3		-	-	0.0
129	GD19100	3		-	-	9.8
135	Ferric reductase transmembrane component, putative	3		-	-	4.9
189	Sulfite reductase Nadph	2		-	-	1.7
146	NADPH--cytochrome P450 reductase 2	2		-	-	41.3
155	NADH-cytochrome b5 reductase	2		-	-	7.9
168	Uncharacterized protein	2		-	-	5.8
163	Ferric reductase-like transmembrane component with cytochrome b-245 motif	2		-	-	37.4
164	Chromosome 1, whole genome shotgun sequence	2		-	-	40.1
199	FRE family ferric-chelate reductase, putative AFU_orthologue AFUA_1G17270	2		-	-	0.0
147	Ferric reductase-like transmembrane component	2		-	-	44.3
175	NADPH-dependent diflavin oxidoreductase	2		-	-	3.7
158	YALI0F29161p	2		-	-	0.0
180	Uncharacterized protein	2		-	-	2.2
197	Ferric reductase-like transmembrane component	2		-	-	0.0
186	Uncharacterized protein	2		-	-	0.0
153	methionine synthase	2		-	-	0.0
149	NADPH-dependent diflavin oxidoreductase 1	2		-	-	0.0
154	NADH-cytochrome b5 reductase	2		-	-	8.2
202	Putative ferric reductase	2		-	-	38.2
181	Ferric reductase NAD binding domain-domain-containing protein	2		-	-	0.0
192	Uncharacterized protein	2		-	-	32.2
191	Superoxide-generating NADPH oxidase heavy chain subunit C	2		-	-	19.0
173	NADPH--cytochrome P450 reductase 2	2		-	-	0.0
178	Ferric-chelate reductase, putative	2		-	-	1.3
182	Uncharacterized protein	2		-	-	0.0
201	Uncharacterized protein	2		-	-	38.8
196	Ferric reduction oxidase 8, mitochondrial	2		-	-	0.0
187	YALI0C21362p	2		-	-	0.0
190	Dihydroorotate dehydrogenase B NAD(+	2		-	-	0.0
165	Ferric-chelate reductase, putative	2		-	-	22.9
200	Uncharacterized protein	2		-	-	37.8
174	Uncharacterized protein	2		-	-	10.3
162	NADH-cytochrome b5 reductase-like	2		-	-	6.5
148	Uncharacterized protein	2		-	-	26.2
159	Iron import ATP-binding/permease protein IrtA	2		-	-	0.0
185	Putative metalloreductase	2		-	-	1.4
167	YALI0F07040p	2		-	-	0.0
179	FAD-binding domain-domain-containing protein	2		-	-	0.0
166	Uncharacterized protein	2		-	-	34.5
160	Ferredoxin:NADP oxidoreductase, beta subunit	2		-	-	6.8
195	YALI0F01386p	2		-	-	0.0
161	NADH-dependent ferredoxin:NADP+ oxidoreductase, beta subunit	2		-	-	0.0
183	Ferric-chelate reductase, putative AFU_orthologue AFUA_6G13750	2		-	-	2.6
156	Predicted protein	2		-	-	0.0
172	Uncharacterized protein	2		-	-	0.0
150	Cytochrome b5 reductase 4	2		-	-	0.0
188	NADPH--cytochrome P450 reductase	2		-	-	0.0
145	Uncharacterized protein	2		-	-	36.5
177	FAD-binding domain-domain-containing protein	2		-	-	0.0
151	NADPH reductase TAH18	2		-	-	0.0
184	Frp1p	2		-	-	0.7
176	FAD-binding domain-domain-containing protein	2		-	-	0.0
152	Uncharacterized protein	2		-	-	2.6
204	Uncharacterized protein	2		-	-	2.2
170	Ferric reductase transmembrane component, putative	2		-	-	0.0
194	YALI0F01386p	2		-	-	0.0
169	Uncharacterized protein	2		-	-	0.0
171	Uncharacterized protein	2		-	-	0.0
193	Ferric reductase-like transmembrane component	2		-	-	0.0
198	FRE family ferric-chelate reductase, putative AFU_orthologue AFUA_1G17270	2		-	-	0.0
203	Ferric-chelate reductase/ oxidoreductase	2		-	-	42.0
157	Uncharacterized protein	2		-	-	3.6
224	NADH-cytochrome b5 reductase	1		-	-	0.0
241	Uncharacterized protein	1		-	-	0.0
237	Uncharacterized protein	1		-	-	0.0
240	Uncharacterized protein	1		-	-	0.0
232	Uncharacterized protein	1		-	-	0.0
228	Putative respiratory burst oxidase homolog protein I	1		-	-	0.0
246	NADPH oxidase 4	1		-	-	0.0
219	Uncharacterized protein	1		-	-	0.0
223	NADH-cytochrome b5 reductase-like protein	1		-	-	0.0
247	NADPH oxidase 4	1		-	-	0.0
231	Uncharacterized protein	1		-	-	0.0
236	Uncharacterized protein	1		-	-	0.0
209	Uncharacterized protein	1		-	-	0.0
242	Sulfite reductase	1		-	-	0.0
230	Uncharacterized protein	1		-	-	0.0
225	Uncharacterized protein	1		-	-	0.0
211	Iron-chelator utilization protein, putative	1		-	-	0.0
207	Uncharacterized protein	1		-	-	0.0
210	Uncharacterized protein	1		-	-	0.0
216	NADH-cytochrome b5 reductase	1		-	-	0.0
217	Uncharacterized protein	1		-	-	0.0
239	Cytochrome b5 reductase 3	1		-	-	0.0
212	Uncharacterized protein	1		-	-	0.0
206	Benzoyl-CoA oxygenase, A subunit	1		-	-	0.0
215	Uncharacterized protein	1		-	-	0.0
221	Ferredoxin:NADP oxidoreductase, beta subunit	1		-	-	0.0
244	Os08g0453700 protein	1		-	-	0.0
243	Uncharacterized protein	1		-	-	0.0
226	Uncharacterized protein	1		-	-	0.0
220	Uncharacterized FAD-binding protein C17H9.12c	1		-	-	0.0
248	Uncharacterized protein	1		-	-	0.0
205	Ferric reductase-like transmembrane component	1		-	-	0.0
234	NADH--cytochrome b5 reductase 1	1		-	-	0.0
227	Uncharacterized protein	1		-	-	0.0
222	Uncharacterized protein	1		-	-	0.0
238	Uncharacterized protein	1		-	-	0.0
233	Uncharacterized protein	1		-	-	0.0
245	NADPH oxidase 5	1		-	-	0.0
214	Uncharacterized protein	1		-	-	0.0
213	Uncharacterized protein	1		-	-	0.0
229	Uncharacterized protein	1		-	-	0.0
218	Uncharacterized protein	1		-	-	0.0
235	Uncharacterized protein	1		-	-	0.0
208	Predicted protein	1		-	-	0.0