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CATH Superfamily 3.40.50.720

NAD(P)-binding Rossmann-like Domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
NAD(P)-binding Rossmann-like Domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 460: 3-oxoacyl-[acyl-carrier-protein] reductase FabG1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
 14 O07399 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS)
(4 more)
NADP binding GO:0050661
Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
 14 O07399 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS)
(4 more)
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
 11 P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 11 P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI) P9WGT3 (/IPI)
(1 more)
Acetoacetyl-CoA reductase activity GO:0018454
Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
 11 P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA)
(1 more)
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
 11 P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA)
(1 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fatty acid elongation GO:0030497
The elongation of a fatty acid chain by the sequential addition of two-carbon units.
 14 O07399 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS) P0A5Y5 (/ISS)
(4 more)
Short-chain fatty acid metabolic process GO:0046459
The chemical reactions and pathways involving fatty acids with a chain length of less than C6.
 11 P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA)
(1 more)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
 11 P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA)
(1 more)
Mycolic acid biosynthetic process GO:0071768
The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
 11 P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA) P9WGT3 (/IDA)
(1 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 11 P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA) P9WGT3 (/HDA)
(1 more)
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