The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"P-loop containing nucleotide triphosphate hydrolases
".
FunFam 520: probable ATP-dependent RNA helicase DDX23
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | P93008 (/IPI) P93008 (/IPI) Q9BUQ8 (/IPI) Q9BUQ8 (/IPI) Q9BUQ8 (/IPI) Q9BUQ8 (/IPI) Q9BUQ8 (/IPI) Q9BUQ8 (/IPI) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
6 | Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
6 | Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) |
|
RNA helicase activity GO:0003724
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
|
3 | Q95SF2 (/ISS) Q9VJ74 (/ISS) Q9Y7T7 (/ISS) |
Showing 1 to 4 of 4 entries
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
8 | Q95SF2 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9VJ74 (/IC) |
|
Cis assembly of pre-catalytic spliceosome GO:0000354
Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
|
6 | Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) Q9BUQ8 (/IC) |
|
RNA splicing, via transesterification reactions GO:0000375
Splicing of RNA via a series of two transesterification reactions.
|
6 | Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
6 | Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) |
|
RNA splicing GO:0008380
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
6 | Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
2 | P93008 (/IMP) P93008 (/IMP) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
2 | Q95SF2 (/ISS) Q9VJ74 (/ISS) |
|
Regulation of defense response to virus GO:0050688
Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
|
2 | Q95SF2 (/IMP) Q9VJ74 (/IMP) |
|
Positive regulation of production of miRNAs involved in gene silencing by miRNA GO:1903800
Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
|
2 | P93008 (/IMP) P93008 (/IMP) |
|
Positive regulation of primary miRNA processing GO:2000636
Any process that activates or increases the frequency, rate or extent of primary microRNA processing.
|
2 | P93008 (/IMP) P93008 (/IMP) |
Showing 1 to 10 of 17 entries
There are 17 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
15 |
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
P93008 (/IDA)
P93008 (/IDA)
Q95QN2 (/IDA)
Q9BUQ8 (/IDA)
(5 more) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
12 |
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
A0A024R0Z3 (/IDA)
Q9BUQ8 (/IDA)
Q9BUQ8 (/IDA)
Q9BUQ8 (/IDA)
Q9BUQ8 (/IDA)
(2 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) Q9BUQ8 (/TAS) |
|
U5 snRNP GO:0005682
A ribonucleoprotein complex that contains small nuclear RNA U5.
|
6 | Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
6 | Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) Q9BUQ8 (/HDA) |
|
Catalytic step 2 spliceosome GO:0071013
A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
|
6 | Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) Q9BUQ8 (/IDA) |
|
U5 snRNP GO:0005682
A ribonucleoprotein complex that contains small nuclear RNA U5.
|
2 | D3Z0M9 (/ISO) Q9Y7T7 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P93008 (/IDA) P93008 (/IDA) |
|
Precatalytic spliceosome GO:0071011
A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
|
2 | Q95SF2 (/HDA) Q9VJ74 (/HDA) |
Showing 1 to 10 of 17 entries
