The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Succinyl-CoA synthetase domains
".
FunFam 3: ATP-citrate synthase subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ATP citrate synthase activity GO:0003878
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.
|
7 | P16638 (/IDA) P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) Q91V92 (/IDA) Q9FGX1 (/IDA) Q9FGX1 (/IDA) |
|
ATP citrate synthase activity GO:0003878
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.
|
5 | Q2TCH3 (/ISS) Q32PF2 (/ISS) Q91V92 (/ISS) Q9C522 (/ISS) Q9C522 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P53396 (/IPI) P53396 (/IPI) P53396 (/IPI) Q91V92 (/IPI) |
|
ATP citrate synthase activity GO:0003878
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
ATP citrate synthase activity GO:0003878
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.
|
2 | Q5BAJ4 (/RCA) Q5BAJ4 (/RCA) |
|
ATP citrate synthase activity GO:0003878
Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.
|
1 | Q91V92 (/ISO) |
|
Lyase activity GO:0016829
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
|
1 | A0A060W7T9 (/IDA) |
Showing 1 to 8 of 8 entries
There are 30 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acetyl-CoA biosynthetic process GO:0006085
The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
|
4 | Q9C522 (/TAS) Q9C522 (/TAS) Q9FGX1 (/TAS) Q9FGX1 (/TAS) |
|
Citrate metabolic process GO:0006101
The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.
|
4 | P16638 (/IDA) P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) |
|
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
|
4 | P16638 (/ISS) Q2TCH3 (/ISS) Q32PF2 (/ISS) Q91V92 (/ISS) |
|
Acetyl-CoA biosynthetic process GO:0006085
The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
|
3 | P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) |
|
Oxaloacetate metabolic process GO:0006107
The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
|
3 | P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) |
|
Cholesterol biosynthetic process GO:0006695
The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
Lipid biosynthetic process GO:0008610
The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
|
3 | P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) |
|
Coenzyme A metabolic process GO:0015936
The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
Positive regulation of cellular metabolic process GO:0031325
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
Showing 1 to 10 of 30 entries
There are 20 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
12 |
A0A024R1T9 (/IDA)
A0A024R1T9 (/IDA)
A0A024R1T9 (/IDA)
A0A024R1Y2 (/IDA)
A0A024R1Y2 (/IDA)
P53396 (/IDA)
P53396 (/IDA)
P53396 (/IDA)
Q9C522 (/IDA)
Q9C522 (/IDA)
(2 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
10 | A0A024R1T9 (/IDA) A0A024R1T9 (/IDA) A0A024R1T9 (/IDA) A0A024R1Y2 (/IDA) A0A024R1Y2 (/IDA) P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) Q9FGX1 (/IDA) Q9FGX1 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
8 | A0A024R1T9 (/IDA) A0A024R1T9 (/IDA) A0A024R1T9 (/IDA) A0A024R1Y2 (/IDA) A0A024R1Y2 (/IDA) P53396 (/IDA) P53396 (/IDA) P53396 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | P16638 (/ISS) Q2TCH3 (/ISS) Q32PF2 (/ISS) Q91V92 (/ISS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | P53396 (/HDA) P53396 (/HDA) P53396 (/HDA) |
|
Azurophil granule lumen GO:0035578
The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
3 | P53396 (/HDA) P53396 (/HDA) P53396 (/HDA) |
|
Ficolin-1-rich granule lumen GO:1904813
Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
|
3 | P53396 (/TAS) P53396 (/TAS) P53396 (/TAS) |
Showing 1 to 10 of 20 entries
