The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Aspartate/ornithine carbamoyltransferase
".
FunFam 9: Ornithine carbamoyltransferase, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
			The search results have been sorted with the annotations that are found most frequently at the top of the
			list. The results can be filtered by typing text into the search box at the top of the table.
			
			
	| GO Term | Annotations | Evidence | 
|---|---|---|
| Ornithine carbamoyltransferase activity GO:0004585 Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. | 9 | P00480 (/IDA) P00481 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) Q9YHY9 (/IDA) | 
| Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | 6 | P05150 (/IPI) P05150 (/IPI) P05150 (/IPI) P05150 (/IPI) P05150 (/IPI) P05150 (/IPI) | 
| Ornithine carbamoyltransferase activity GO:0004585 Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. | 2 | P00481 (/IMP) P31317 (/IMP) | 
| Ornithine carbamoyltransferase activity GO:0004585 Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Phospholipid binding GO:0005543 Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Amino acid binding GO:0016597 Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Phosphate ion binding GO:0042301 Interacting selectively and non-covalently with phosphate. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Phospholipid binding GO:0005543 Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester. | 1 | P00481 (/IDA) | 
| Amino acid binding GO:0016597 Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents. | 1 | P00481 (/IMP) | 
| Phosphate ion binding GO:0042301 Interacting selectively and non-covalently with phosphate. | 1 | P00481 (/IMP) | 
There are 27 GO terms relating to "biological process"
			The search results have been sorted with the annotations that are found most frequently at the top of the
			list. The results can be filtered by typing text into the search box at the top of the table.
			
			
	| GO Term | Annotations | Evidence | 
|---|---|---|
| Arginine biosynthetic process GO:0006526 The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid. | 9 | P05150 (/IMP) P05150 (/IMP) P05150 (/IMP) P05150 (/IMP) P05150 (/IMP) P05150 (/IMP) Q4WNW5 (/IMP) Q4WNW5 (/IMP) Q4WNW5 (/IMP) | 
| Urea cycle GO:0000050 The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. | 2 | P00480 (/IDA) P00481 (/IDA) | 
| Urea cycle GO:0000050 The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Ornithine metabolic process GO:0006591 The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Ornithine catabolic process GO:0006593 The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Citrulline biosynthetic process GO:0019240 The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. | 2 | P00480 (/IDA) P00481 (/IDA) | 
| Citrulline biosynthetic process GO:0019240 The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Anion homeostasis GO:0055081 Any process involved in the maintenance of an internal steady state of anions within an organism or cell. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Protein homotrimerization GO:0070207 The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Ammonia homeostasis GO:0097272 Any biological process involved in the maintenance of an internal steady state of ammonia. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Urea cycle GO:0000050 The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. | 1 | P31317 (/IC) | 
| Urea cycle GO:0000050 The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate. | 1 | P00480 (/TAS) | 
| Liver development GO:0001889 The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. | 1 | P00481 (/IEP) | 
| Arginine metabolic process GO:0006525 The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid. | 1 | Q9YHY9 (/TAS) | 
| Ornithine metabolic process GO:0006591 The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. | 1 | P00481 (/IDA) | 
| Ornithine catabolic process GO:0006593 The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis. | 1 | P00480 (/IDA) | 
| Midgut development GO:0007494 The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. | 1 | P00481 (/IEP) | 
| Response to zinc ion GO:0010043 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus. | 1 | P00481 (/IEP) | 
| Response to nutrient levels GO:0031667 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. | 1 | P00481 (/IEP) | 
| Response to insulin GO:0032868 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. | 1 | P00481 (/IEP) | 
| Arginine biosynthetic process via ornithine GO:0042450 The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine. | 1 | P31317 (/IMP) | 
| Arginine biosynthetic process via ornithine GO:0042450 The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine. | 1 | Q9YHY9 (/NAS) | 
| Response to drug GO:0042493 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease. | 1 | P00481 (/IEP) | 
| Anion homeostasis GO:0055081 Any process involved in the maintenance of an internal steady state of anions within an organism or cell. | 1 | P00481 (/IDA) | 
| Protein homotrimerization GO:0070207 The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits. | 1 | P00481 (/IDA) | 
| Response to biotin GO:0070781 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus. | 1 | P00481 (/IEP) | 
| Ammonia homeostasis GO:0097272 Any biological process involved in the maintenance of an internal steady state of ammonia. | 1 | P00480 (/IMP) | 
There are 14 GO terms relating to "cellular component"
			The search results have been sorted with the annotations that are found most frequently at the top of the
			list. The results can be filtered by typing text into the search box at the top of the table.
			
			
	| GO Term | Annotations | Evidence | 
|---|---|---|
| Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. | 6 | P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) P05150 (/IDA) | 
| Mitochondrion GO:0005739 A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | 3 | P00480 (/IDA) P00481 (/IDA) P31317 (/IDA) | 
| Mitochondrion GO:0005739 A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | 3 | O19072 (/ISS) P84010 (/ISS) Q9N1U7 (/ISS) | 
| Mitochondrial inner membrane GO:0005743 The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. | 3 | O19072 (/ISS) P84010 (/ISS) Q9N1U7 (/ISS) | 
| Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Mitochondrion GO:0005739 A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | 2 | P11725 (/HDA) P11725 (/HDA) | 
| Mitochondrion GO:0005739 A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Mitochondrial inner membrane GO:0005743 The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. | 2 | P11725 (/HDA) P11725 (/HDA) | 
| Mitochondrial inner membrane GO:0005743 The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. | 2 | P11725 (/ISO) P11725 (/ISO) | 
| Mitochondrial matrix GO:0005759 The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. | 2 | P00480 (/TAS) Q9YHY9 (/TAS) | 
| Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | 1 | P31317 (/HDA) | 
| Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | 1 | P00481 (/IDA) | 
| Mitochondrial inner membrane GO:0005743 The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. | 1 | P00481 (/IDA) | 
| Mitochondrial matrix GO:0005759 The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. | 1 | P00480 (/NAS) | 
