The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: NADH-quinone oxidoreductase subunit B 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
5 Q83BQ6 (/ISS) Q83BQ6 (/ISS) Q83BQ6 (/ISS) Q83BQ6 (/ISS) Q83BQ6 (/ISS)
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).
3 O75251 (/NAS) O75251 (/NAS) Q5ADP7 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O75251 (/IPI) O75251 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q42577 (/IDA) Q42577 (/IDA)
Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor GO:0016655
Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
2 O75251 (/NAS) O75251 (/NAS)
NADH dehydrogenase (quinone) activity GO:0050136
Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
2 Q5LPR4 (/ISS) Q5LPR4 (/ISS)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
1 Q5RJN0 (/IPI)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
1 Q9DC70 (/ISO)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
11 P0CB83 (/ISS) P0CB83 (/ISS) P0CB84 (/ISS) P0CB84 (/ISS) P42026 (/ISS) Q0MQH9 (/ISS) Q0MQH9 (/ISS) Q0MQI0 (/ISS) Q0MQI0 (/ISS) Q0MQI0 (/ISS)
(1 more)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
5 Q83BQ6 (/ISS) Q83BQ6 (/ISS) Q83BQ6 (/ISS) Q83BQ6 (/ISS) Q83BQ6 (/ISS)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
2 O75251 (/NAS) O75251 (/NAS)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
2 O75251 (/TAS) O75251 (/TAS)
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
2 O75251 (/IMP) O75251 (/IMP)
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
2 O75251 (/TAS) O75251 (/TAS)
Mitochondrial electron transport, NADH to ubiquinone GO:0006120
The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
1 Q94360 (/IC)
Mitochondrial respiratory chain complex I assembly GO:0032981
The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
1 Q9DC70 (/ISO)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
12 P0CB83 (/ISS) P0CB83 (/ISS) P0CB84 (/ISS) P0CB84 (/ISS) P42026 (/ISS) Q0MQH9 (/ISS) Q0MQH9 (/ISS) Q0MQI0 (/ISS) Q0MQI0 (/ISS) Q0MQI0 (/ISS)
(2 more)
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
5 O75251 (/IDA) O75251 (/IDA) P42026 (/IDA) Q42577 (/IDA) Q42577 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q42577 (/IDA) Q42577 (/IDA)
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2 O75251 (/IMP) O75251 (/IMP)
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
2 O75251 (/NAS) O75251 (/NAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
2 O75251 (/TAS) O75251 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9DC70 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q54NI6 (/ISS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q9DC70 (/HDA)
Mitochondrial respiratory chain complex I GO:0005747
A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
1 Q9DC70 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q5ADP7 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q5RJN0 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q9DC70 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q5RJN0 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q9DC70 (/ISO)
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
1 Q5RJN0 (/IDA)
Synaptic membrane GO:0097060
A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
1 Q9DC70 (/ISO)
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