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CATH Superfamily 3.40.50.1220

TPP-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
TPP-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Electron transfer flavoprotein, alpha subunitElectron transfer flavoprotein subunit alpha, mitochondrialSC:2NAD-dependent histone deacetylase sirtuin-1NAD-dependent protein deacylaseNAD-dependent histone deacetylase SIR2SC:32-hydroxyacyl-CoA lyase 1Pyruvate dehydrogenase [ubiquinone]N(2)-(2-carboxyethyl)arginine synthaseBranched-chain alpha-ketoacid decarboxylaseSC:4NAD-dependent deacetylase sirtuin-22-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseNAD-dependent protein deacetylase sirtuin-6NAD-dependent protein deacetylase HST2NAD-dependent protein deacetylase sirtuin-3, mitochondrialNAD(P) transhydrogenase subunit betaNAD-dependent protein deacylase 1Electron transfer flavoproteinAcetolactate synthasePyruvate decarboxylase 1NAD-dependent deacetylase sirtuin-7Acetolactate synthaseNAD-dependent protein deacetylase SRT1SIR2 family histone deacetylaseNAD-dependent histone deacetylase SIR2Pyruvate decarboxylase isozymeNAD-dependent protein deacetylase sirtuin-1Nad-dependent histone deacetylase sir2-like proteinIlvB (bacterial acetolactate synthase)-likeElectron transfer flavoprotein, alpha subunitElectron transfer flavoprotein, alpha subunit2-hydroxyacyl-CoA lyasePyruvate decarboxylaseNAD-dependent protein deacetylase sirtuin-2Unplaced genomic scaffold supercont1.13, whole genome shotgun sequenceAcetolactate synthase, catabolicNAD-dependent protein deacetylase sirtuin-6 isoform X2Transcriptional regulatory protein sir2bAlpha-keto acid decarboxylase family proteinElectron transfer flavoprotein subunit alphaNAD-dependent histone deacetylase HST3Electron transfer flavoprotein alpha subunit apoproteinTranscriptional regulatory protein sir2bNAD-dependent protein deacetylase sirtuin-6 isoform X22-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolaseAlpha-keto-acid decarboxylaseNAD-dependent protein deacetylasePutative indole-3-pyruvate decarboxylaseUnplaced genomic scaffold supercont1.7, whole genome shotgun sequenceElectron-transfer-flavoprotein, alpha polypeptide, putativeElectron transfer flavoprotein alpha subunitNAD-dependent deacetylase, Sir2 family proteinPyruvate decarboxylase, putativePutative 2-hydroxyacyl-CoA lyasePhenylpyruvate decarboxylasePutative acetolactate synthase IlvGThi3pPyruvate decarboxylase, putativeAcetyl-CoA decarbonylase/synthase complex subunit epsilonDeacetylase SIR2NAD-dependent protein deacetylase sirtuin-6 isoform X32-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthaseNAD-dependent protein deacetylaseNAD-dependent deacetylase sir2E2-oxoglutarate decarboxylase/hydro-lyase/magnesium ion-binding proteinSIR2 family proteinSir2 family transcriptional regulator putativeNAD-dependent protein deacetylase sir-2.4NAD-dependent histone deacetylase Sir2Electron transfer flavoprotein subunit alphaPutative acetolactate synthase large subunitTranscriptional regulator, Sir2 family proteinPutative pyruvate/indole-pyruvate carboxylaseHst3pNicotinamide nucleotide transhydrogenaseElectron transfer flavoprotein subunit alphaRelated to NAD-dependent histone deacetylaseNAD-dependent deacetylase, Sir2 family proteinSirtuin type 2Probable electron transfer flavoprotein alpha subunitElectron transfer flavoprotein subunit alpha, mitochondrialFormyltransferase/hydrolase complex Fhc subunit BChromosome 16, whole genome shotgun sequencePyruvate oxidaseRelated to NAD-dependent histone deacetylaseProbable 2-hydroxyacyl-CoA lyase 1Sulfoacetaldehyde acetyltransferaseADR254WpAcetolactate synthase, large subunit, putativePhenylpyruvate decarboxylaseThiamine diphosphate-binding proteinDHS-like NAD/FAD-binding domain-containing proteinNAD-dependent protein deacylase SIR2rp2DHS-like NAD/FAD-binding domain-containing proteinUncharacterized proteinElectron transfer flavoprotein alpha subunitElectron transfer flavoprotein alpha-subunitUncharacterized protein2-hydroxyphytanoyl-CoA lyase, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinACR211WpPutative 2-hydroxyacyl-CoA lyasePutative indolepyruvate decarboxylase, isozyme 1Putative pyruvate decarboxylase C3G9.11cUncharacterized proteinTranscriptional regulator, Sir2 family proteinUncharacterized proteinHistone deacetylase HDAC silent information regulator protein 2 Sir2 sirtuinTranscriptional regulator, Sir2 family proteinNAD-dependent protein deacetylaseNAD-dependent histone deacetylase sir2Uncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinSir2-type regulatory transcription factor silent information regulator proteinUncharacterized proteinUncharacterized proteinTranscriptional regulatorSir2-type regulatory transcription factor silent information regulator proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinNAD-dependent deacetylase sir2BUncharacterized proteinUncharacterized proteinUncharacterized proteinThiamine diphosphate dependent-3-acetyloctanal synthase PigDSirtuin 7Pyruvate decarboxylaseUncharacterized proteinSirtuin 1Uncharacterized protein
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FunFam 24: 2-hydroxyacyl-CoA lyase

GO Diversity

Unique GO annotations
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1 Unique GO terms

EC Diversity

Unique EC annotations
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1 Unique EC terms

Species Diversity

Unique species annotations
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35 Unique species

Statistics

Members
CATH Domains: 0
Sequences: 40
Annotations
Unique GO: 1
Unique EC: 1
Unique Species: 35
Representative
Rep ID: Q9LF46/203-356
Inherited Annotations: 0
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