The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"TPP-binding domain
".
FunFam 13: Pyruvate dehydrogenase [ubiquinone]
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
|
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
|
Thiamine pyrophosphate binding GO:0030976
Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
10 | P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) P07003 (/IPI) |
|
Flavin adenine dinucleotide binding GO:0050660
Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
|
Pyruvate dehydrogenase (quinone) activity GO:0052737
Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
|
10 | P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) |
|
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
|
10 | Q48HU2 (/ISS) Q48HU2 (/ISS) Q48HU2 (/ISS) Q882W2 (/ISS) Q882W2 (/ISS) Q882W2 (/ISS) Q882W2 (/ISS) Q882W2 (/ISS) Q882W2 (/ISS) Q882W2 (/ISS) |
|
Pyruvate catabolic process GO:0042867
The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.
|
10 | P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) P07003 (/IMP) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
|
Arginine catabolic process to succinate GO:0019545
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.
|
1 | Q9HUI8 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) P07003 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) P07003 (/IDA) |
