The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Glutaredoxin
".
FunFam 3: Peroxiredoxin 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 41 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
|
48 |
H2KZL7 (/IDA)
O74887 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
(38 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
42 |
O08807 (/IPI)
O74887 (/IPI)
P0CB50 (/IPI)
P30048 (/IPI)
P30048 (/IPI)
P30048 (/IPI)
P30048 (/IPI)
P30048 (/IPI)
P32119 (/IPI)
P32119 (/IPI)
(32 more) |
Peroxiredoxin activity GO:0051920
Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
|
21 |
O74887 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
Q04120 (/IDA)
Q04120 (/IDA)
(11 more) |
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
|
19 |
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
(9 more) |
Thioredoxin peroxidase activity GO:0008379
Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
|
15 |
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
Q04120 (/IMP)
Q04120 (/IMP)
Q04120 (/IMP)
(5 more) |
Antioxidant activity GO:0016209
Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
|
15 |
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
(5 more) |
Trypanothione-disulfide reductase activity GO:0015042
Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.
|
14 |
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q71RY2 (/ISA)
Q71RY2 (/ISA)
Q71RY2 (/ISA)
(4 more) |
Antioxidant activity GO:0016209
Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
|
14 |
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
(4 more) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
9 | P20108 (/IPI) P30048 (/IPI) P30048 (/IPI) P30048 (/IPI) P30048 (/IPI) P30048 (/IPI) P35700 (/IPI) P35700 (/IPI) P35705 (/IPI) |
Peroxidase activity GO:0004601
Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
|
8 | O74887 (/IDA) Q06830 (/IDA) Q06830 (/IDA) Q06830 (/IDA) Q06830 (/IDA) Q95NF5 (/IDA) Q95NF5 (/IDA) Q9NL98 (/IDA) |
Showing 1 to 10 of 41 entries
There are 129 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
29 |
P20108 (/IMP)
P30048 (/IMP)
P30048 (/IMP)
P30048 (/IMP)
P30048 (/IMP)
P30048 (/IMP)
P32119 (/IMP)
P32119 (/IMP)
P32119 (/IMP)
P32119 (/IMP)
(19 more) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
26 |
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
P32119 (/IDA)
(16 more) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
23 |
P30048 (/TAS)
P30048 (/TAS)
P30048 (/TAS)
P30048 (/TAS)
P30048 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
(13 more) |
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
19 |
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
Q04120 (/IDA)
Q04120 (/IDA)
Q04120 (/IDA)
(9 more) |
Hydrogen peroxide catabolic process GO:0042744
The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
|
17 |
H2KZL7 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
Q06830 (/IDA)
Q06830 (/IDA)
Q06830 (/IDA)
Q06830 (/IDA)
(7 more) |
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
|
16 |
O74887 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
Q04120 (/IMP)
Q04120 (/IMP)
(6 more) |
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
|
15 |
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
Q04120 (/IDA)
Q04120 (/IDA)
Q04120 (/IDA)
(5 more) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
15 |
P34760 (/IGI)
P34760 (/IGI)
P34760 (/IGI)
P34760 (/IGI)
P34760 (/IGI)
P34760 (/IGI)
P34760 (/IGI)
Q04120 (/IGI)
Q04120 (/IGI)
Q04120 (/IGI)
(5 more) |
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
15 |
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
P34760 (/IMP)
Q04120 (/IMP)
Q04120 (/IMP)
Q04120 (/IMP)
(5 more) |
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
14 |
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
P32119 (/NAS)
(4 more) |
Showing 1 to 10 of 129 entries
There are 51 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
41 |
H2KZL7 (/IDA)
O08807 (/IDA)
O74887 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
(31 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
23 |
O08807 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P30048 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
P34760 (/IDA)
(13 more) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
22 |
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
P32119 (/HDA)
(12 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
21 |
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
(11 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
14 |
Q06830 (/IDA)
Q06830 (/IDA)
Q06830 (/IDA)
Q06830 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
(4 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
14 |
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q38EX8 (/ISA)
Q71RY2 (/ISA)
Q71RY2 (/ISA)
Q71RY2 (/ISA)
(4 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
14 |
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
P32119 (/TAS)
(4 more) |
Glycosome GO:0020015
A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
|
14 |
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q38EX8 (/IDA)
Q71RY2 (/IDA)
Q71RY2 (/IDA)
Q71RY2 (/IDA)
(4 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | O74887 (/HDA) Q06830 (/HDA) Q06830 (/HDA) Q06830 (/HDA) Q06830 (/HDA) Q13162 (/HDA) Q13162 (/HDA) Q13162 (/HDA) Q13162 (/HDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
7 | Q38EX8 (/IDA) Q38EX8 (/IDA) Q38EX8 (/IDA) Q38EX8 (/IDA) Q38EX8 (/IDA) Q38EX8 (/IDA) Q38EX8 (/IDA) |
Showing 1 to 10 of 51 entries