The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Decaprenyl diphosphate synthase-like
".
FunFam 8: NUS1, dehydrodolichyl diphosphate synthase subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Prenyltransferase activity GO:0004659
Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).
|
1 | Q99LJ8 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q96E22 (/IPI) |
|
Dehydrodolichyl diphosphate synthase activity GO:0045547
Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.
|
1 | Q96E22 (/IDA) |
|
Dehydrodolichyl diphosphate synthase activity GO:0045547
Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.
|
1 | Q99LJ8 (/ISO) |
|
Dehydrodolichyl diphosphate synthase activity GO:0045547
Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.
|
1 | Q99LJ8 (/ISS) |
There are 19 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.
|
1 | Q6DHR8 (/IMP) |
|
Dolichyl diphosphate biosynthetic process GO:0006489
The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.
|
1 | Q96E22 (/IDA) |
|
Dolichyl diphosphate biosynthetic process GO:0006489
The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.
|
1 | Q99LJ8 (/ISO) |
|
Dolichyl diphosphate biosynthetic process GO:0006489
The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.
|
1 | Q99LJ8 (/ISS) |
|
Dolichyl diphosphate biosynthetic process GO:0006489
The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.
|
1 | Q96E22 (/TAS) |
|
Dolichol biosynthetic process GO:0019408
The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
|
1 | Q96E22 (/IMP) |
|
Dolichol biosynthetic process GO:0019408
The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
|
1 | Q99LJ8 (/ISO) |
|
Regulation of intracellular cholesterol transport GO:0032383
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
|
1 | Q96E22 (/IGI) |
|
Regulation of intracellular cholesterol transport GO:0032383
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
|
1 | Q99LJ8 (/IMP) |
|
Regulation of intracellular cholesterol transport GO:0032383
Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
|
1 | Q99LJ8 (/ISO) |
|
Protein mannosylation GO:0035268
The addition of a mannose residue to a protein acceptor molecule.
|
1 | Q99LJ8 (/IMP) |
|
Vascular endothelial growth factor signaling pathway GO:0038084
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q96E22 (/IMP) |
|
Vascular endothelial growth factor signaling pathway GO:0038084
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | Q99LJ8 (/ISO) |
|
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
|
1 | Q99LJ8 (/IMP) |
|
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
|
1 | Q96E22 (/IMP) |
|
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
|
1 | Q99LJ8 (/ISO) |
|
Positive regulation of nitric-oxide synthase activity GO:0051000
Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
|
1 | Q96E22 (/IMP) |
|
Positive regulation of nitric-oxide synthase activity GO:0051000
Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
|
1 | Q99LJ8 (/ISO) |
|
Sterol homeostasis GO:0055092
Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
|
1 | Q99LJ8 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q96E22 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q99LJ8 (/ISO) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q96E22 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q99LJ8 (/IMP) |
|
Dehydrodolichyl diphosphate synthase complex GO:1904423
A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.
|
1 | Q96E22 (/IDA) |
|
Dehydrodolichyl diphosphate synthase complex GO:1904423
A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.
|
1 | Q99LJ8 (/ISO) |
|
Dehydrodolichyl diphosphate synthase complex GO:1904423
A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.
|
1 | Q99LJ8 (/ISS) |
