The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Metalloenzyme, LuxS/M16 peptidase-like
".
FunFam 3: Insulin-degrading enzyme
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Insulysin.
[EC: 3.4.24.56]
Degradation of insulin, glucagon and other polypeptides. No action on proteins.
|
5 | P14735 P22817 P35559 Q24K02 Q9JHR7 |
|
Nardilysin.
[EC: 3.4.24.61]
Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys.
|
4 | A0A178WD59 A0A178WD59 F4HNU6 F4HNU6 |
