The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"TFB5-like
".
FunFam 1: General transcription factor IIH subunit 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
44 |
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
Q6ZYL4 (/IPI)
(34 more) |
RDNA binding GO:0000182
Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA.
|
1 | Q8K2X8 (/IDA) |
Showing 1 to 2 of 2 entries
There are 28 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleotide-excision repair GO:0006289
A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
|
45 |
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
Q6ZYL4 (/IMP)
(35 more) |
Nucleotide-excision repair, DNA duplex unwinding GO:0000717
The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Transcription-coupled nucleotide-excision repair GO:0006283
The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Nucleotide-excision repair, preincision complex stabilization GO:0006293
The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Nucleotide-excision repair, preincision complex assembly GO:0006294
The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Nucleotide-excision repair, DNA incision, 3'-to lesion GO:0006295
The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Nucleotide-excision repair, DNA incision, 5'-to lesion GO:0006296
The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Transcription initiation from RNA polymerase I promoter GO:0006361
Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Transcription elongation from RNA polymerase I promoter GO:0006362
The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Termination of RNA polymerase I transcription GO:0006363
The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.
|
44 |
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
Q6ZYL4 (/TAS)
(34 more) |
Showing 1 to 10 of 28 entries
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
58 |
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
Q5ZKH0 (/TAS)
(48 more) |
Transcription factor TFIID complex GO:0005669
A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
|
44 |
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
Q6ZYL4 (/IDA)
(34 more) |
Transcription factor TFIIH core complex GO:0000439
The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
|
6 | B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) |
Transcription factor TFIIH holo complex GO:0005675
A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.
|
6 | B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) B7Z018 (/IDA) |
Transcription factor TFIID complex GO:0005669
A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
|
1 | Q8K2X8 (/ISO) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q8K2X8 (/IDA) |
Showing 1 to 7 of 7 entries