CATH Superfamily 3.30.60.20

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Protein unc-13 homolog B	1208	3D	1y8fA00	-	71.5
2	Diacylglycerol kinase	1145	3D	1r79A01	-	94.1
3	Protein kinase C delta	933	3D	3uglB01	-	89.9
4	B-Raf proto-oncogene serine/threonine-protein kinase	892	3D	1farA00	-	91.4
5	Non-specific serine/threonine protein kinase	806		-	-	87.6
6	Protein kinase C	663	3D	2e73A01	-	74.9
7	Serine/threonine-protein kinase	584		-	-	74.9
8	Protein kinase C theta	546	3D	2yuuA00	-	86.0
9	Diacylglycerol kinase	511		-	-	25.8
10	Putative kinase suppressor of Ras 1	504	3D	1kbfA00	-	78.5
11	Protein kinase C	495	3D	1tboA00	-	55.2
12	Protein kinase C	487		-	-	88.9
13	Diacylglycerol kinase	422		-	-	85.2
14	Protein kinase C	417		-	-	78.7
15	Vav guanine nucleotide exchange factor 1	408	3D	2vrwB03	-	86.8
16	Diacylglycerol kinase	392		-	-	75.0
17	Thymidine kinase	380		-	-	72.7
18	Citron rho-interacting serine/threonine kinase	357		-	-	78.3
19	Serine/threonine-protein kinase	345		-	-	68.2
20	Putative unconventional myosin-IXa	335		-	-	77.9
21	Serine/threonine-protein kinase	328		-	-	88.9
22	SH3 and cysteine-rich domain-containing protein 3 isoform 2	318	3D	2db6A01	-	86.4
23	RAS guanyl-releasing protein 1 isoform X1	307	3D	4l9mA04	-	83.2
24	Protein kinase C epsilon	296		-	-	77.4
25	Chimaerin	273		-	-	91.3
26	Thymidine kinase	247	3D	3e2iA02	-	79.9
28	Thymidine kinase	245	3D	2wvjH02	-	85.0
27	Diacylglycerol kinase	222		-	-	87.0
30	Chimaerin	216	3D	3cxlA02	-	48.4
29	Diacylglycerol kinase	214		-	-	71.2
31	Protein kinase C alpha	198	3D	2eliA01	-	70.8
32	rho guanine nucleotide exchange factor 2 isoform X2	190		-	-	29.2
33	Rac GTPase-activating protein 1	189	3D	4b6dF00	-	92.3
34	Protein kinase C	172		-	-	74.5
35	Diacylglycerol kinase	163		-	-	18.2
36	Rho-associated protein kinase 1	144	3D	2rowA01	-	79.4
37	RAS guanyl releasing protein 4	134		-	-	81.8
38	A-kinase anchor protein 13 isoform X1	126		-	-	50.7
39	Diacylglycerol kinase	124		-	-	73.4
41	Diacylglycerol kinase	124		-	-	32.5
40	Actin polymerization protein Bzz1	124		-	-	83.3
42	differentially expressed in FDCP 8 homolog isoform X2	123		-	-	47.4
43	Diacylglycerol kinase	122		-	-	65.4
44	SH3 and cysteine-rich domain-containing protein	118		-	-	57.5
45	Rho-associated protein kinase 2	113		-	-	50.6
46	Rho GTPase-activating protein 29	98		-	-	35.4
47	Diacylglycerol kinase	95		-	-	44.0
48	Thymidine kinase	84		-	-	84.4
51	Thymidine kinase	79	3D	5fuyF02	-	88.7
49	serine/threonine-protein kinase MRCK gamma isoform X2	76		-	-	74.0
50	Rho guanine nucleotide exchange factor 28	68		-	-	66.4
52	Protein kinase C	58		-	-	74.9
53	Diacylglycerol kinase	58		-	-	77.8
54	Diacylglycerol kinase	56		-	-	62.6
56	Uncharacterized protein, isoform C	55		-	-	63.5
55	PDZ domain-containing protein 8	55		-	-	37.3
57	Ras association domain family member 5	54	3D	2fnfX01	-	47.1
58	Diacylglycerol kinase	47		-	-	77.3
59	Tensin 2	47		-	-	48.8
61	Kinase suppressor of Ras	44		-	-	81.8
60	Diacylglycerol kinase	44		-	-	49.5
62	Thymidine kinase	40		-	-	49.3
63	Protein kinase C	36		-	-	73.1
64	Protein kinase C	36		-	-	81.2
65	Tensin 1	34		-	-	81.0
66	Diacylglycerol kinase	32		-	-	51.1
67	uncharacterized protein LOC108093793 isoform X1	22		-	-	11.2
68	Serine/threonine-protein kinase D2	21		-	-	61.9
83	Thymidine kinase	21	3D	4uxjH02	-	13.2
86	Thymidine kinase	18	3D	2qqeB02	-	14.8
69	SET domain binding factor	17		-	-	13.9
70	Uncharacterized protein, isoform B	16		-	-	11.3
71	Protein kinase C	16		-	-	80.0
72	Protein kinase C	14		-	-	20.6
73	Protein kinase C	14		-	-	19.5
77	Diacylglycerol kinase	13		-	-	7.2
74	Thymidine kinase	13		-	-	16.6
76	Diacylglycerol kinase	13		-	-	11.7
75	Rho-associated protein kinase 1	13		-	-	25.6
78	Protein CBG14248	12		-	-	9.9
79	Heavy chain, Unconventional Myosin	11		-	-	13.0
80	Serine/threonine-protein kinase dkf-1	10		-	-	20.9
81	Diacylglycerol kinase	10		-	-	47.2
82	Diacylglycerol kinase	10		-	-	54.8
84	Diacylglycerol kinase	9		-	-	29.8
85	Rap Guanine nucleotide Exchange Factor homolog	9		-	-	7.5
87	Ras association domain family member 1	8		-	-	32.9
93	Related to ser/thr protein kinase	7		-	-	17.6
88	Protein kinase C	7		-	-	19.6
89	Diacylglycerol kinase	7		-	-	19.8
92	Diacylglycerol kinase	7		-	-	6.0
91	Diacylglycerol kinase	7		-	-	60.4
94	Diacylglycerol kinase	7		-	-	9.6
90	Diacylglycerol kinase	7		-	-	52.0
101	Diacylglycerol kinase	6		-	-	2.3
96	Protein kinase D, isoform H	6		-	-	66.9
99	Diacylglycerol kinase	6		-	-	0.0
95	Thymidine kinase	6		-	-	11.7
98	Diacylglycerol kinase	6		-	-	3.3
100	Diacylglycerol kinase	6		-	-	3.8
97	CYtoKinesis defect	6		-	-	14.8
108	Protein kinase C	5		-	-	75.6
107	Non-specific serine/threonine protein kinase	5		-	-	8.4
105	Diacylglycerol kinase	5		-	-	70.7
106	Diacylglycerol kinase	5		-	-	79.4
102	Protein kinase C	5		-	-	3.8
104	Rho-associated protein kinase let-502	5		-	-	26.4
103	Phorbol esters/diacylglycerol binding domain C1 domain	5		-	-	5.2
111	CBN-KSR-1 protein	4		-	-	13.0
110	Diacylglycerol kinase	4		-	-	0.0
113	Kinase suppressor of ras 1	4		-	-	5.0
109	Signal transducer	4		-	-	0.0
112	Diacylglycerol kinase	4		-	-	4.4
118	Diacylglycerol kinase	3		-	-	61.2
121	Probable serine/threonine-protein kinase DDB_G0288147	3		-	-	82.5
117	Protein kinase D2	3		-	-	37.0
116	Diacylglycerol kinase	3		-	-	39.4
122	Protein kinase C	3		-	-	38.6
115	PRKD2 isoform 13	3		-	-	0.0
123	Serine/threonine-protein kinase dkf-2	3		-	-	42.0
114	Thymidine kinase	3		-	-	0.0
120	Diacylglycerol kinase A	3		-	-	69.7
119	AGAP005583-PA	3		-	-	12.1
136	Heavy chain, Unconventional Myosin	2		-	-	14.5
135	Diacylglycerol kinase	2		-	-	5.4
130	Rho kinase	2		-	-	0.0
127	Uncharacterized protein	2		-	-	0.0
134	Protein kinase C	2		-	-	0.0
133	Chromosome 10, whole genome shotgun sequence	2		-	-	8.3
132	Uncharacterized protein	2		-	-	8.1
128	Diacylglycerol kinase	2		-	-	47.2
129	AGAP006932-PA	2		-	-	4.0
124	Serine/threonine-protein kinase pakD	2		-	-	21.7
131	Uncharacterized protein	2		-	-	0.0
125	Diacylglycerol kinase A	2		-	-	29.3
126	Protein kinase D4	2		-	-	51.3
156	Probable Rho-type GTPase-activating protein 3	1		-	-	0.0
148	Diacylglycerol kinase	1		-	-	0.0
160	Protein kinase C	1		-	-	0.0
141	Uncharacterized protein	1		-	-	0.0
150	Diacylglycerol kinase	1		-	-	0.0
155	Uncharacterized protein	1		-	-	0.0
163	Serine/threonine protein kinase BRAF	1		-	-	0.0
154	Protein kinase D4	1		-	-	0.0
153	Predicted protein	1		-	-	0.0
164	Uncharacterized protein	1		-	-	0.0
147	Diacylglycerol kinase	1		-	-	0.0
162	Uncharacterized protein	1		-	-	0.0
159	Uncharacterized protein	1		-	-	0.0
152	Diacylglycerol kinase	1		-	-	0.0
139	Uncharacterized protein	1		-	-	0.0
146	Diacylglycerol kinase gamma	1		-	-	0.0
158	Diacylglycerol kinase	1		-	-	0.0
138	Thymidine kinase	1		-	-	0.0
151	Ankyrin repeat-containing protein kinase A	1		-	-	0.0
140	Protein kinase C, putative	1		-	-	0.0
161	SH3 and cysteine rich domain	1		-	-	0.0
145	Kinase suppressor of Ras B	1		-	-	0.0
144	Uncharacterized protein	1		-	-	0.0
157	Protein vav-1	1		-	-	0.0
137	Thymidine kinase	1		-	-	0.0
143	Predicted protein	1		-	-	0.0
142	Predicted protein	1		-	-	0.0
149	Diacylglycerol kinase	1		-	-	0.0

Network disruptions

Functional Families

Browse Functional Families