The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Thymidylate synthase/dCMP hydroxymethylase domain
".
FunFam 5: Thymidylate synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Thymidylate synthase activity GO:0004799
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
|
5 | P06785 (/IDA) P06785 (/IDA) P06785 (/IDA) P06785 (/IDA) P06785 (/IDA) |
|
Thymidylate synthase activity GO:0004799
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
|
5 | P06785 (/IMP) P06785 (/IMP) P06785 (/IMP) P06785 (/IMP) P06785 (/IMP) |
|
Thymidylate synthase activity GO:0004799
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
|
1 | C8VB77 (/RCA) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DTMP biosynthetic process GO:0006231
The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
|
5 | P06785 (/IMP) P06785 (/IMP) P06785 (/IMP) P06785 (/IMP) P06785 (/IMP) |
|
Nucleobase-containing compound metabolic process GO:0006139
Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
|
1 | C8VB77 (/RCA) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
|
5 | P06785 (/IDA) P06785 (/IDA) P06785 (/IDA) P06785 (/IDA) P06785 (/IDA) |
