The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Thymidylate synthase/dCMP hydroxymethylase domain
".
FunFam 2: Possible thymidylate synthase
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
Thymidylate synthase.
[EC: 2.1.1.45]
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
|
26 |
A0A178UZ11
A0A178UZ11
B7FA29
B7FA29
B7FA29
B8BPG2
B8BPG2
B8BPG2
O81395
P04818 (16 more...) |
Dihydrofolate reductase.
[EC: 1.5.1.3]
5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH.
|
16 |
A0A178UZ11
A0A178UZ11
B7FA29
B7FA29
B7FA29
B8BPG2
B8BPG2
B8BPG2
O81395
P51820 (6 more...) |