The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Dynein light chain 2a, cytoplasmic
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Dynein light chain roadblock

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q22752 (/IPI) Q22752 (/IPI) Q22752 (/IPI) Q9VQA6 (/IPI)
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
3 Q388T6 (/ISA) Q388T6 (/ISA) Q4QDU1 (/ISA)
Dynein intermediate chain binding GO:0045505
Interacting selectively and non-covalently with an intermediate chain of the dynein complex.
1 Q9VQA6 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
3 Q388T6 (/ISA) Q388T6 (/ISA) Q4QDU1 (/ISA)
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
1 Q9VQA6 (/ISS)
Cilium movement involved in cell motility GO:0060294
Movement of cilia mediated by motor proteins that contributes to the movement of a cell.
1 Q9SWQ6 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Cytoplasmic dynein complex GO:0005868
Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
3 Q388T6 (/ISA) Q388T6 (/ISA) Q4QDU1 (/ISA)
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
3 Q388T6 (/ISO) Q388T6 (/ISO) Q4QDU1 (/ISO)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 Q22752 (/IDA) Q22752 (/IDA) Q22752 (/IDA)
Dynein complex GO:0030286
Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
1 Q9VQA6 (/ISS)
Outer dynein arm GO:0036157
Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
1 Q9SWQ6 (/IDA)
Outer dynein arm GO:0036157
Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
1 Q9SWQ6 (/IGI)
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