The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 68: Ectonucleoside triphosphate diphosphohydrolase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Nucleoside-diphosphatase activity GO:0017110
Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.
6 O55026 (/IDA) O55026 (/IDA) P55772 (/IDA) P55772 (/IDA) Q8BFW6 (/IDA) Q8K0L2 (/IDA)
Nucleoside-triphosphatase activity GO:0017111
Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
6 O55026 (/IDA) O55026 (/IDA) P55772 (/IDA) P55772 (/IDA) Q8BFW6 (/IDA) Q8K0L2 (/IDA)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
5 A0A1D5PS27 (/IDA) O35795 (/IDA) P79784 (/IDA) P97687 (/IDA) Q9USP2 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 O55026 (/IPI) O55026 (/IPI) O75355 (/IPI) P49961 (/IPI)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
4 O55026 (/ISO) O55026 (/ISO) P55772 (/ISO) P55772 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 O55026 (/ISO) O55026 (/ISO) P55772 (/ISO) P55772 (/ISO)
Adenosine-diphosphatase activity GO:0043262
Catalysis of the reaction: ADP + H2O = AMP + phosphate.
4 O55026 (/ISO) O55026 (/ISO) P55772 (/ISO) P55772 (/ISO)
Adenosine-diphosphatase activity GO:0043262
Catalysis of the reaction: ADP + H2O = AMP + phosphate.
3 O35795 (/IDA) P97687 (/IDA) Q9USP2 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 O35795 (/IDA) P97687 (/IDA)
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
1 Q9USP2 (/IDA)
Showing 1 to 10 of 14 entries

There are 34 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
9 E7FG27 (/IDA) F1Q7R9 (/IDA) F1QSE5 (/IDA) F1RDI7 (/IDA) F8W5L6 (/IDA) Q66L64 (/IDA) Q6DC46 (/IDA) Q6ZM68 (/IDA) Q6ZM69 (/IDA)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
9 E7FG27 (/IDA) F1Q7R9 (/IDA) F1QSE5 (/IDA) F1RDI7 (/IDA) F8W5L6 (/IDA) Q66L64 (/IDA) Q6DC46 (/IDA) Q6ZM68 (/IDA) Q6ZM69 (/IDA)
Cellular response to methanol GO:0071405
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.
6 E7FG27 (/IDA) F1Q7R9 (/IDA) F1QSE5 (/IDA) F8W5L6 (/IDA) Q6DC46 (/IDA) Q6ZM69 (/IDA)
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
4 O55026 (/IDA) O55026 (/IDA) P55772 (/IDA) P55772 (/IDA)
Purine ribonucleoside diphosphate catabolic process GO:0009181
The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
4 O55026 (/IDA) O55026 (/IDA) P55772 (/IDA) P55772 (/IDA)
Platelet activation GO:0030168
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
4 O55026 (/IDA) O55026 (/IDA) P55772 (/IDA) P55772 (/IDA)
Nucleobase-containing small molecule catabolic process GO:0034656
The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
4 O75355 (/TAS) P49961 (/TAS) Q5MY95 (/TAS) Q9Y5L3 (/TAS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
4 O55026 (/ISO) O55026 (/ISO) P55772 (/ISO) P55772 (/ISO)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
2 O35795 (/IEP) P97687 (/IEP)
Negative regulation of dopamine secretion GO:0033602
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.
2 P55772 (/ISO) P55772 (/ISO)
Showing 1 to 10 of 34 entries

There are 31 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
4 O55026 (/IDA) O55026 (/IDA) P55772 (/IDA) P55772 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 O35795 (/IDA) O55026 (/IDA) O55026 (/IDA) Q8BFW6 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 O75355 (/TAS) P49961 (/TAS) Q5MY95 (/TAS) Q9Y5L3 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
4 O55026 (/ISO) O55026 (/ISO) P55772 (/ISO) P55772 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P55772 (/ISO) P55772 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 O55026 (/ISO) O55026 (/ISO)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2 P55772 (/ISO) P55772 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 O35795 (/IDA) P97687 (/IDA)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
2 P55772 (/ISO) P55772 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P79784 (/IDA) Q8K0L2 (/IDA)
Showing 1 to 10 of 31 entries
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