The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 148: Actin, alpha skeletal muscle

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)
Mesenchyme migration GO:0090131
The process in which the population of cells that make up a mesenchyme undergo directed movement.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)
Myosin filament GO:0032982
A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
50 G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS) G1QHI9 (/ISS)
(40 more)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
12 A0A091D4C3 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 A0A091D4C3 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS)
(2 more)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
12 A0A091D4C3 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS)
(2 more)
Dense body GO:0097433
An electron dense body which may contain granules.
12 A0A091D4C3 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS) H0VKP1 (/ISS)
(2 more)
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