The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
TCP-1-like chaperonin intermediate domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: T-complex protein 1 subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
28 P47207 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI)
(18 more)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
13 P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI) P78371 (/IPI)
(3 more)
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
13 P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA)
(3 more)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
13 P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS)
(3 more)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
4 P39076 (/IDA) P39076 (/IDA) P39076 (/IDA) P39076 (/IDA)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
4 Q386W9 (/ISA) Q386W9 (/ISA) Q386W9 (/ISA) Q386W9 (/ISA)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
2 P80314 (/ISO) P80314 (/ISO)
Protein folding chaperone GO:0044183
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
2 P80314 (/ISO) P80314 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q10147 (/ISM)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
1 Q10147 (/ISO)
Showing 1 to 10 of 11 entries

There are 30 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
13 P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS)
(3 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
13 P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS)
(3 more)
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
13 P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS)
(3 more)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
Chaperone mediated protein folding independent of cofactor GO:0051086
The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
Chaperone-mediated protein complex assembly GO:0051131
The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
ScaRNA localization to Cajal body GO:0090666
A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
Positive regulation of establishment of protein localization to telomere GO:1904851
Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.
13 P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP) P78371 (/IMP)
(3 more)
Showing 1 to 10 of 30 entries

There are 31 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
31 F5GWF6 (/IDA) F5GWF6 (/IDA) F5GWF6 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA)
(21 more)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
21 P39076 (/IDA) P39076 (/IDA) P39076 (/IDA) P39076 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA)
(11 more)
Chaperonin-containing T-complex GO:0005832
A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
17 Q3ZBH0 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS) Q4R6F8 (/ISS)
(7 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
14 B6V9S9 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS)
(4 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
13 P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS)
(3 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
13 P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS) P78371 (/NAS)
(3 more)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
13 P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA) P78371 (/IDA)
(3 more)
Azurophil granule lumen GO:0035578
The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
13 P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS) P78371 (/TAS)
(3 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
13 P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA) P78371 (/HDA)
(3 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P39076 (/HDA) P39076 (/HDA) P39076 (/HDA) P39076 (/HDA) Q9W392 (/HDA)
Showing 1 to 10 of 31 entries
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