The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phox-like domain
".
FunFam 40: NADPH oxidase organizer 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8NFA2 (/IPI) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
1 | Q8NFA2 (/TAS) |
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
1 | Q8VCM2 (/IDA) |
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
1 | Q8NFA2 (/TAS) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q8NFA2 (/IPI) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | Q8VCM2 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
|
1 | Q8VCM2 (/IDA) |
|
Regulation of hydrogen peroxide metabolic process GO:0010310
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
|
1 | Q8NFA2 (/TAS) |
|
Extracellular matrix disassembly GO:0022617
A process that results in the breakdown of the extracellular matrix.
|
1 | Q8NFA2 (/IMP) |
|
Extracellular matrix disassembly GO:0022617
A process that results in the breakdown of the extracellular matrix.
|
1 | Q8VCM2 (/ISO) |
|
Extracellular matrix disassembly GO:0022617
A process that results in the breakdown of the extracellular matrix.
|
1 | Q8VCM2 (/ISS) |
|
Regulation of respiratory burst GO:0060263
Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
|
1 | Q8NFA2 (/TAS) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8NFA2 (/TAS) |
|
NADPH oxidase complex GO:0043020
A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
|
1 | Q8NFA2 (/IDA) |
|
NADPH oxidase complex GO:0043020
A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
|
1 | Q8VCM2 (/ISO) |
