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CATH Superfamily 3.30.1240.20

Eukaryotic phosphomannomutase, cap domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Eukaryotic phosphomannomutase, cap domain

Phosphomannomutase (PMM) catalyses the conversion of mannose-6-phosphate to mannose-1-phosphate, an essential step in mannose activation and the biosynthesis of glycoconjugates in all eukaryotes PMID:16963079. Bacterial alpha-phosphoglucomutases share an overall fold similar to that of eukaryotic phosphomannomutases PMID:24100319. PMM can be divided into two domains: the cap and core. This entry represents the cap domain. The heart of the cap domain is a four-stranded antiparallel beta-sheet elaborated on one face with three alpha-helices PMID:16963079.

PMID:16963079 PMID:24100319

GO Diversity

Unique GO annotations
24 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
2313 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 21
Domain clusters (>95% seq id): 6
Domain clusters (>35% seq id): 2
Unique PDBs: 14
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 4
Function
Unique EC: 1
Unique GO: 24
Taxonomy
Unique Species: 2313
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