The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Bactericidal permeability-increasing protein; domain 2
".
FunFam 1: Phospholipid transfer protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 38 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
|
6 | P17213 (/IDA) P17454 (/IDA) P18428 (/IDA) Q61805 (/IDA) Q63313 (/IDA) Q6AXU0 (/IDA) |
|
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
|
2 | Q61805 (/ISO) Q67E05 (/ISO) |
|
Lipopolysaccharide binding GO:0001530
Interacting selectively and non-covalently with lipopolysaccharide.
|
2 | P18428 (/ISS) Q2TBI0 (/ISS) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P17454 (/IDA) Q61805 (/IDA) |
|
Lipid transporter activity GO:0005319
Enables the directed movement of lipids into, out of or within a cell, or between cells.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Phospholipid transporter activity GO:0005548
Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Phosphatidylethanolamine binding GO:0008429
Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Phosphatidylcholine transporter activity GO:0008525
Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
|
2 | P55058 (/IDA) Q8WMN7 (/IDA) |
|
Phosphatidylcholine transporter activity GO:0008525
Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Diacylglycerol binding GO:0019992
Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids.
|
2 | P55065 (/ISO) P55065 (/ISO) |
Showing 1 to 10 of 38 entries
There are 99 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Macrophage activation involved in immune response GO:0002281
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
|
3 | P18428 (/ISS) Q2TBI0 (/ISS) Q63313 (/ISS) |
|
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
|
3 | P17454 (/IDA) P18428 (/IDA) Q61805 (/IDA) |
|
Positive regulation of tumor necrosis factor production GO:0032760
Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
|
3 | P18428 (/ISS) Q2TBI0 (/ISS) Q63313 (/ISS) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
3 | Q2TBI0 (/ISS) Q61805 (/ISS) Q63313 (/ISS) |
|
Macrophage activation involved in immune response GO:0002281
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
|
2 | P17454 (/IDA) Q61805 (/IDA) |
|
Lipid transport GO:0006869
The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Opsonization GO:0008228
The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.
|
2 | P18428 (/IC) Q61805 (/IC) |
|
Vitamin E biosynthetic process GO:0010189
The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
|
2 | P55065 (/IMP) P55065 (/IMP) |
|
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Phospholipid transport GO:0015914
The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
|
2 | P55065 (/ISO) P55065 (/ISO) |
Showing 1 to 10 of 99 entries
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
5 | P17454 (/IDA) P18428 (/IDA) Q61805 (/IDA) Q63313 (/IDA) Q8WMN7 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
3 | P17213 (/TAS) P18428 (/TAS) P55058 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
3 | P55058 (/HDA) P55065 (/HDA) P55065 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P18428 (/ISS) Q2TBI0 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q67E05 (/IDA) Q6AXU0 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P18428 (/IDA) Q61805 (/IDA) |
|
High-density lipoprotein particle GO:0034364
A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
|
2 | P55065 (/ISO) P55065 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
2 | P17213 (/HDA) P18428 (/HDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q61805 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q67E05 (/ISO) |
Showing 1 to 10 of 14 entries
