The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ski
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Dachshund homolog 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q24027 (/IPI) Q9QYB2 (/IPI) Q9UI36 (/IPI)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
1 Q9UI36 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
1 Q9QYB2 (/ISO)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q9UI36 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q9QYB2 (/ISO)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q9QYB2 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q96NX9 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q96NX9 (/NAS)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q9UI36 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q9QYB2 (/ISO)
Showing 1 to 10 of 11 entries

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
12 Q24027 (/TAS) Q24028 (/TAS) Q24029 (/TAS) Q24030 (/TAS) Q24031 (/TAS) Q59DY9 (/TAS) Q59DZ0 (/TAS) Q6NR49 (/TAS) Q8IP19 (/TAS) Q8IP20 (/TAS)
(2 more)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
12 Q24027 (/IMP) Q24028 (/IMP) Q24029 (/IMP) Q24030 (/IMP) Q24031 (/IMP) Q59DY9 (/IMP) Q59DZ0 (/IMP) Q6NR49 (/IMP) Q8IP19 (/IMP) Q8IP20 (/IMP)
(2 more)
Leg disc proximal/distal pattern formation GO:0007479
The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.
12 Q24027 (/TAS) Q24028 (/TAS) Q24029 (/TAS) Q24030 (/TAS) Q24031 (/TAS) Q59DY9 (/TAS) Q59DZ0 (/TAS) Q6NR49 (/TAS) Q8IP19 (/TAS) Q8IP20 (/TAS)
(2 more)
Genital disc morphogenesis GO:0007483
The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.
12 Q24027 (/TAS) Q24028 (/TAS) Q24029 (/TAS) Q24030 (/TAS) Q24031 (/TAS) Q59DY9 (/TAS) Q59DZ0 (/TAS) Q6NR49 (/TAS) Q8IP19 (/TAS) Q8IP20 (/TAS)
(2 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
12 Q24027 (/IMP) Q24028 (/IMP) Q24029 (/IMP) Q24030 (/IMP) Q24031 (/IMP) Q59DY9 (/IMP) Q59DZ0 (/IMP) Q6NR49 (/IMP) Q8IP19 (/IMP) Q8IP20 (/IMP)
(2 more)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
12 Q24027 (/IEP) Q24028 (/IEP) Q24029 (/IEP) Q24030 (/IEP) Q24031 (/IEP) Q59DY9 (/IEP) Q59DZ0 (/IEP) Q6NR49 (/IEP) Q8IP19 (/IEP) Q8IP20 (/IEP)
(2 more)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
12 Q24027 (/IMP) Q24028 (/IMP) Q24029 (/IMP) Q24030 (/IMP) Q24031 (/IMP) Q59DY9 (/IMP) Q59DZ0 (/IMP) Q6NR49 (/IMP) Q8IP19 (/IMP) Q8IP20 (/IMP)
(2 more)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
12 Q24027 (/IMP) Q24028 (/IMP) Q24029 (/IMP) Q24030 (/IMP) Q24031 (/IMP) Q59DY9 (/IMP) Q59DZ0 (/IMP) Q6NR49 (/IMP) Q8IP19 (/IMP) Q8IP20 (/IMP)
(2 more)
Spermathecum morphogenesis GO:0035211
The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.
12 Q24027 (/TAS) Q24028 (/TAS) Q24029 (/TAS) Q24030 (/TAS) Q24031 (/TAS) Q59DY9 (/TAS) Q59DZ0 (/TAS) Q6NR49 (/TAS) Q8IP19 (/TAS) Q8IP20 (/TAS)
(2 more)
Genital disc development GO:0035215
Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.
12 Q24027 (/TAS) Q24028 (/TAS) Q24029 (/TAS) Q24030 (/TAS) Q24031 (/TAS) Q59DY9 (/TAS) Q59DZ0 (/TAS) Q6NR49 (/TAS) Q8IP19 (/TAS) Q8IP20 (/TAS)
(2 more)
Showing 1 to 10 of 40 entries

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 Q24027 (/IDA) Q24028 (/IDA) Q24029 (/IDA) Q24030 (/IDA) Q24031 (/IDA) Q59DY9 (/IDA) Q59DZ0 (/IDA) Q6NR49 (/IDA) Q8IP19 (/IDA) Q8IP20 (/IDA)
(3 more)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 Q9QYB2 (/IDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 Q9QYB2 (/IPI)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9QYB2 (/IDA)
Showing 1 to 4 of 4 entries
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