CATH Superfamily 3.10.20.90
Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
".
FunFam 107: protein DDI1 homolog 2 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | Q5TDH0 (/IPI) Q5TDH0 (/IPI) Q5TDH0 (/IPI) Q5TDH0 (/IPI) Q5TDH0 (/IPI) Q5TDH0 (/IPI) Q8WTU0 (/IPI) |
|
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
6 | Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
6 | Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) |
|
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
|
6 | Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) |
|
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
4 | A2ADY9 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
4 | A2ADY9 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) |
|
Aspartic-type endopeptidase activity GO:0004190
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
|
1 | A2ADY9 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | A2ADY9 (/ISO) |
|
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
|
1 | A2ADY9 (/ISO) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Proteasomal protein catabolic process GO:0010498
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
|
10 | A0JPP7 (/ISS) A2ADY9 (/ISS) Q2T9Z1 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q9DAF3 (/ISS) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
10 | A0JPP7 (/ISS) A2ADY9 (/ISS) Q2T9Z1 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q9DAF3 (/ISS) |
|
Cellular response to hydroxyurea GO:0072711
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
10 | A0JPP7 (/ISS) A2ADY9 (/ISS) Q2T9Z1 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q9DAF3 (/ISS) |
|
Regulation of DNA stability GO:0097752
Any process that modulates the stability of DNA.
|
10 | A0JPP7 (/ISS) A2ADY9 (/ISS) Q2T9Z1 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q95JI3 (/ISS) Q9DAF3 (/ISS) |
|
Proteasomal protein catabolic process GO:0010498
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
|
7 | Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q8WTU0 (/IMP) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
7 | Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q8WTU0 (/IMP) |
|
Cellular response to hydroxyurea GO:0072711
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
7 | Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q8WTU0 (/IMP) |
|
Regulation of DNA stability GO:0097752
Any process that modulates the stability of DNA.
|
7 | Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q8WTU0 (/IMP) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
6 | Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
6 | Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) Q5TDH0 (/IMP) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
4 | A2ADY9 (/ISS) Q497D6 (/ISS) Q6TH22 (/ISS) Q7ZYA7 (/ISS) |
|
Proteasomal protein catabolic process GO:0010498
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
|
2 | A2ADY9 (/ISO) Q9DAF3 (/ISO) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
2 | A2ADY9 (/ISO) Q9DAF3 (/ISO) |
|
Cellular response to hydroxyurea GO:0072711
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
|
2 | A2ADY9 (/ISO) Q9DAF3 (/ISO) |
|
Regulation of DNA stability GO:0097752
Any process that modulates the stability of DNA.
|
2 | A2ADY9 (/ISO) Q9DAF3 (/ISO) |
|
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
|
1 | A2ADY9 (/ISO) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) Q5TDH0 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | A2ADY9 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | A2ADY9 (/ISO) |
