The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cytochrome b5-like heme/steroid binding domain
".
FunFam 21: Delta(8)-fatty-acid desaturase 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
|
2 | O96099 (/IDA) Q9Y1W0 (/IDA) |
|
Oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water GO:0016717
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.
|
2 | A9SIZ6 (/IDA) A9SIZ6 (/IDA) |
|
Sphingolipid delta-8 desaturase activity GO:0052631
Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).
|
2 | Q9ZRP7 (/IDA) Q9ZRP7 (/IDA) |
|
Sphingolipid delta-8 desaturase activity GO:0052631
Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).
|
1 | Q3EBF7 (/IMP) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Unsaturated fatty acid biosynthetic process GO:0006636
The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
|
4 | A9SIZ6 (/IDA) A9SIZ6 (/IDA) O96099 (/IDA) Q9Y1W0 (/IDA) |
|
Sphingolipid biosynthetic process GO:0030148
The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
|
3 | Q3EBF7 (/IMP) Q9ZRP7 (/IMP) Q9ZRP7 (/IMP) |
|
Cellular response to cold GO:0070417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
3 | Q3EBF7 (/IMP) Q9ZRP7 (/IMP) Q9ZRP7 (/IMP) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
2 | Q9ZRP7 (/IDA) Q9ZRP7 (/IDA) |
|
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
|
2 | A9SIZ6 (/IDA) A9SIZ6 (/IDA) |
|
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
|
1 | Q9Y1W0 (/IMP) |
|
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | Q9Y1W0 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
3 | Q3EBF7 (/IDA) Q9ZRP7 (/IDA) Q9ZRP7 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O96099 (/IC) Q9Y1W0 (/IC) |
