The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cytochrome b5-like heme/steroid binding domain
".
FunFam 10: Delta-6 fatty acyl desaturase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Linoleoyl-CoA desaturase activity GO:0016213
Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.
|
6 | I3NL78 (/IMP) Q6QDP0 (/IMP) Q6SES0 (/IMP) Q8AY64 (/IMP) Q98SW7 (/IMP) Q9DEX6 (/IMP) |
|
Linoleoyl-CoA desaturase activity GO:0016213
Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.
|
3 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) |
|
Stearoyl-CoA 9-desaturase activity GO:0004768
Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O.
|
1 | Q9Z0R9 (/IDA) |
|
Stearoyl-CoA 9-desaturase activity GO:0004768
Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O.
|
1 | Q9Z122 (/TAS) |
|
Omega-6 fatty acid desaturase activity GO:0045485
Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.
|
1 | Q9Z122 (/TAS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Unsaturated fatty acid biosynthetic process GO:0006636
The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
|
11 |
B7U6V1 (/IMP)
D2KE02 (/IMP)
D2KE03 (/IMP)
D2Y364 (/IMP)
I3NL78 (/IMP)
Q4TVM9 (/IMP)
Q6QDP0 (/IMP)
Q8AY64 (/IMP)
Q8QGE2 (/IMP)
Q98SW7 (/IMP)
(1 more) |
|
Alpha-linolenic acid metabolic process GO:0036109
The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
|
6 | I3NL78 (/IMP) Q6QDP0 (/IMP) Q8AY64 (/IMP) Q8QGE2 (/IMP) Q98SW7 (/IMP) Q9DEX6 (/IMP) |
|
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
|
5 | I3NL78 (/IMP) Q6QDP0 (/IMP) Q8AY64 (/IMP) Q98SW7 (/IMP) Q9DEX6 (/IMP) |
|
Unsaturated fatty acid biosynthetic process GO:0006636
The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
|
3 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) |
|
Alpha-linolenic acid metabolic process GO:0036109
The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
|
3 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) |
|
Linoleic acid metabolic process GO:0043651
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
|
3 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) |
|
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
|
1 | Q9DEX7 (/IMP) |
|
Very long-chain fatty acid biosynthetic process GO:0042761
The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22.
|
1 | Q9Z122 (/TAS) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
4 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) Q9Z122 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) Q9Z0R9 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O95864 (/TAS) O95864 (/TAS) O95864 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | O95864 (/HDA) O95864 (/HDA) O95864 (/HDA) |
