The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Mannose-Binding Protein A, subunit A
".
FunFam 44: CD209 antigen, isoform CRA_b
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mannose binding GO:0005537
Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
|
8 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) Q91ZW7 (/IDA) Q91ZW7 (/IDA) Q91ZW8 (/IDA) Q91ZW8 (/IDA) Q91ZW9 (/IDA) Q91ZX1 (/IDA) |
|
(1->3)-beta-D-glucan binding GO:0001872
Interacting selectively and non-covalently with (1->3)-beta-D-glucans.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Polysaccharide binding GO:0030247
Interacting selectively and non-covalently with any polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Peptide antigen binding GO:0042605
Interacting selectively and non-covalently with an antigen peptide.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q91ZW8 (/IPI) Q91ZW8 (/IPI) |
|
Virion binding GO:0046790
Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope.
|
2 | Q9H2X3 (/TAS) Q9NNX6 (/TAS) |
|
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
|
1 | Q9H2X3 (/IDA) |
|
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
|
1 | Q9H2X3 (/IMP) |
|
Virus receptor activity GO:0001618
Combining with a virus component and mediating entry of the virus into the cell.
|
1 | Q91ZX1 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9NNX6 (/IPI) |
|
Mannose binding GO:0005537
Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
|
1 | Q9NNX6 (/TAS) |
|
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
|
1 | Q91ZX1 (/ISS) |
|
ICAM-3 receptor activity GO:0030369
Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.
|
1 | Q9H2X3 (/NAS) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
1 | Q9H2X3 (/NAS) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
1 | Q9H2X3 (/IPI) |
|
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
1 | Q91ZX1 (/ISO) |
|
Carbohydrate derivative binding GO:0097367
Interacting selectively and non-covalently with a carbohydrate derivative.
|
1 | Q91ZX1 (/IDA) |
There are 26 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
4 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) Q91ZW8 (/IDA) Q91ZW8 (/IDA) |
|
Detection of yeast GO:0001879
The series of events in which a stimulus from a yeast is received and converted into a molecular signal.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Phagocytosis, recognition GO:0006910
The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Leukocyte cell-cell adhesion GO:0007159
The attachment of a leukocyte to another cell via adhesion molecules.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Cell-cell recognition GO:0009988
Cell recognition between cells. May involve the formation of specialized cell junctions.
|
2 | Q9H2X3 (/TAS) Q9NNX6 (/TAS) |
|
Detection of bacterium GO:0016045
The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Modulation by virus of host morphology or physiology GO:0019048
The process in which a virus effects a change in the structure or processes of its host organism.
|
2 | Q9H2X3 (/TAS) Q9NNX6 (/TAS) |
|
Virion attachment to host cell GO:0019062
The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.
|
2 | Q9H2X3 (/TAS) Q9NNX6 (/TAS) |
|
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Antigen processing and presentation GO:0019882
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
2 | Q91ZW7 (/ISO) Q91ZW7 (/ISO) |
|
Positive regulation of tumor necrosis factor biosynthetic process GO:0042535
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
2 | Q91ZW8 (/IMP) Q91ZW8 (/IMP) |
|
Peptide antigen transport GO:0046968
The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Positive regulation of cytokine secretion GO:0050715
Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell.
|
2 | Q91ZW8 (/IDA) Q91ZW8 (/IDA) |
|
Positive regulation of cytokine secretion GO:0050715
Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell.
|
2 | Q91ZW8 (/IGI) Q91ZW8 (/IGI) |
|
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
|
2 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) |
|
Intracellular transport of virus GO:0075733
The directed movement of a virus, or part of a virus, within the host cell.
|
2 | Q9H2X3 (/TAS) Q9NNX6 (/TAS) |
|
B cell adhesion GO:0097323
The attachment of a B cell to another cell via adhesion molecules.
|
2 | Q91ZW7 (/ISO) Q91ZW7 (/ISO) |
|
Stimulatory C-type lectin receptor signaling pathway GO:0002223
Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.
|
1 | Q9NNX6 (/TAS) |
|
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
|
1 | Q9NNX6 (/TAS) |
|
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
|
1 | Q9NNX6 (/IDA) |
|
Regulation of T cell proliferation GO:0042129
Any process that modulates the frequency, rate or extent of T cell proliferation.
|
1 | Q9NNX6 (/IDA) |
|
Regulation of T cell proliferation GO:0042129
Any process that modulates the frequency, rate or extent of T cell proliferation.
|
1 | Q91ZX1 (/ISO) |
|
B cell adhesion GO:0097323
The attachment of a B cell to another cell via adhesion molecules.
|
1 | Q9NNX6 (/IDA) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q91ZW7 (/ISS) Q91ZW7 (/ISS) Q91ZW8 (/ISS) Q91ZW8 (/ISS) Q91ZX1 (/ISS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
3 | Q8CJ91 (/IDA) Q8CJ91 (/IDA) Q9NNX6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q9H2X3 (/NAS) Q9NNX6 (/NAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q91ZW7 (/ISO) Q91ZW7 (/ISO) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q91ZW7 (/ISO) Q91ZW7 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9H2X3 (/TAS) Q9NNX6 (/TAS) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q8CJ91 (/TAS) Q8CJ91 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9NNX6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9NNX6 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9H2X3 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q9NNX6 (/HDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | Q91ZX1 (/IDA) |
