The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Mannose-Binding Protein A, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Hyaluronan proteoglycan link protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 21 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 A2CF10 (/IPI) A4JYH5 (/IPI) A4JYN2 (/IPI) A4JYN2 (/IPI) A4JYQ1 (/IPI) P13608 (/IPI) P13608 (/IPI) P16112 (/IPI) P16112 (/IPI) P98066 (/IPI)
(4 more)
Extracellular matrix structural constituent conferring compression resistance GO:0030021
A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.
5 P10915 (/RCA) P10915 (/RCA) P16112 (/RCA) P16112 (/RCA) Q9QUP5 (/RCA)
Low-density lipoprotein particle receptor activity GO:0005041
Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
3 Q8R4U0 (/ISO) Q8R4U0 (/ISO) Q8R4Y4 (/ISO)
Scavenger receptor activity GO:0005044
Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).
3 Q8R4U0 (/ISO) Q8R4U0 (/ISO) Q8R4Y4 (/ISO)
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
3 Q8R4U0 (/ISS) Q8R4U0 (/ISS) Q8WWQ8 (/ISS)
Low-density lipoprotein particle binding GO:0030169
Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.
3 Q8R4U0 (/ISO) Q8R4U0 (/ISO) Q8R4Y4 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 A2CF10 (/IDA) A4JYH5 (/IDA) A4JYQ1 (/IDA)
Low-density lipoprotein particle receptor activity GO:0005041
Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
2 Q8WWQ8 (/IDA) Q9NY15 (/IDA)
Scavenger receptor activity GO:0005044
Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).
2 Q8WWQ8 (/IDA) Q9NY15 (/IDA)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
2 P16112 (/TAS) P16112 (/TAS)
Showing 1 to 10 of 21 entries

There are 76 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
9 A0A0B5JFG6 (/IMP) A5PKS6 (/IMP) B3DIH3 (/IMP) F1R511 (/IMP) F1R511 (/IMP) F8W252 (/IMP) F8W252 (/IMP) Q1LXE1 (/IMP) Q60H44 (/IMP)
Positive regulation of lymphangiogenesis GO:1901492
Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.
9 A0A2R8PZT1 (/IMP) A0A2R8Q5U0 (/IMP) A0A2R8RX33 (/IMP) A8KBK2 (/IMP) C6GHV6 (/IMP) E0CZJ3 (/IMP) E7EYE0 (/IMP) F1R1R8 (/IMP) F6P8Y7 (/IMP)
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
8 A0A2R8PZT1 (/IGI) A0A2R8Q5U0 (/IGI) A0A2R8RX33 (/IGI) A8KBK2 (/IGI) C6GHV6 (/IGI) E7EYE0 (/IGI) F1R1R8 (/IGI) F6P8Y7 (/IGI)
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
8 A0A2R8PZT1 (/IMP) A0A2R8Q5U0 (/IMP) A0A2R8RX33 (/IMP) A8KBK2 (/IMP) C6GHV6 (/IMP) E7EYE0 (/IMP) F1R1R8 (/IMP) F6P8Y7 (/IMP)
Blood vessel endothelial cell differentiation GO:0060837
The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.
8 A0A2R8PZT1 (/IMP) A0A2R8Q5U0 (/IMP) A0A2R8RX33 (/IMP) A8KBK2 (/IMP) C6GHV6 (/IMP) E7EYE0 (/IMP) F1R1R8 (/IMP) F6P8Y7 (/IMP)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
6 P10915 (/TAS) P10915 (/TAS) P16112 (/TAS) P16112 (/TAS) Q96GW7 (/TAS) Q96GW7 (/TAS)
Fin regeneration GO:0031101
The regrowth of fin tissue following its loss or destruction.
5 A0A0B5JFG6 (/IGI) A5PKS6 (/IGI) B3DIH3 (/IGI) Q1LXE1 (/IGI) Q60H44 (/IGI)
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
4 E7F537 (/IMP) E7F537 (/IMP) F1QDA1 (/IMP) F1QDA1 (/IMP)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
3 Q8R4U0 (/ISS) Q8R4U0 (/ISS) Q8WWQ8 (/ISS)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
3 Q8R4U0 (/ISO) Q8R4U0 (/ISO) Q8R4Y4 (/ISO)
Showing 1 to 10 of 76 entries

There are 51 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
9 P10915 (/TAS) P10915 (/TAS) P13608 (/TAS) P13608 (/TAS) P16112 (/TAS) P16112 (/TAS) P98066 (/TAS) Q96GW7 (/TAS) Q96GW7 (/TAS)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
7 Q61282 (/IDA) Q61282 (/IDA) Q61361 (/IDA) Q61361 (/IDA) Q9ESM3 (/IDA) Q9ESM3 (/IDA) Q9QUP5 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
6 B0BN34 (/IDA) M0R4G8 (/IDA) P07897 (/IDA) P07897 (/IDA) P55068 (/IDA) P55068 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
6 O08859 (/ISO) O08859 (/ISO) Q61282 (/ISO) Q61282 (/ISO) Q61361 (/ISO) Q61361 (/ISO)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
6 P55068 (/IDA) P55068 (/IDA) Q61282 (/IDA) Q61282 (/IDA) Q61361 (/IDA) Q61361 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
5 P10915 (/HDA) P10915 (/HDA) P16112 (/HDA) P16112 (/HDA) Q9QUP5 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q61282 (/HDA) Q61282 (/HDA) Q96S86 (/HDA) Q96S86 (/HDA)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
4 P16112 (/TAS) P16112 (/TAS) Q96GW7 (/TAS) Q96GW7 (/TAS)
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
4 P16112 (/TAS) P16112 (/TAS) Q96GW7 (/TAS) Q96GW7 (/TAS)
Perineuronal net GO:0072534
A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.
4 P07897 (/IDA) P07897 (/IDA) P55068 (/IDA) P55068 (/IDA)
Showing 1 to 10 of 51 entries
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