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CATH Superfamily 2.70.160.11

Hnrnp arginine n-methyltransferase1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Hnrnp arginine n-methyltransferase1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: Protein arginine N-methyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Type III protein arginine methyltransferase. [EC: 2.1.1.321]
S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L- homocysteine + [protein]-N(omega)-methyl-L-arginine.
  • Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein.
  • Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further.
  • Cf. EC 2.1.1.319, EC 2.1.1.320 and EC 2.1.1.322.
  • Formerly EC 2.1.1.23, EC 2.1.1.124, EC 2.1.1.125 and EC 2.1.1.126.
 14 A0A024R726 A0A024R726 A0A1L8GKH8 A0A1L8GKH8 A2AV36 A6QQV6 Q5U4E8 Q5ZIB9 Q6PCI6 Q6PCI6
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