The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cupredoxins - blue copper proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 57: Ephrin A4

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transmembrane-ephrin receptor activity GO:0005005
Combining with a transmembrane ephrin to initiate a change in cell activity.
4 P52798 (/TAS) P52798 (/TAS) P52798 (/TAS) P52798 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P52798 (/IPI) P52798 (/IPI) P52798 (/IPI) P52798 (/IPI)
Ephrin receptor binding GO:0046875
Interacting selectively and non-covalently with an ephrin receptor.
4 P52798 (/IPI) P52798 (/IPI) P52798 (/IPI) P52798 (/IPI)
Ephrin receptor binding GO:0046875
Interacting selectively and non-covalently with an ephrin receptor.
2 O08542 (/ISO) O08542 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
4 P52798 (/TAS) P52798 (/TAS) P52798 (/TAS) P52798 (/TAS)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
4 P52798 (/TAS) P52798 (/TAS) P52798 (/TAS) P52798 (/TAS)
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
1 Q98TZ1 (/IMP)
Collateral sprouting GO:0048668
The process in which outgrowths develop from the shafts of existing axons.
1 Q98TZ1 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P52798 (/TAS) P52798 (/TAS) P52798 (/TAS) P52798 (/TAS)
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
4 P52798 (/TAS) P52798 (/TAS) P52798 (/TAS) P52798 (/TAS)
CATH-Gene3D is a Global Biodata Core Resource Learn more...