The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 43: roundabout homolog 2 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
18 |
A0A2R8QRK0 (/IPI)
A4JYD3 (/IPI)
A4JYH1 (/IPI)
A8DZ85 (/IPI)
F1QBD4 (/IPI)
F1QFK4 (/IPI)
O55005 (/IPI)
O89026 (/IPI)
Q90Z69 (/IPI)
Q90Z70 (/IPI)
(8 more) |
|
Axon guidance receptor activity GO:0008046
Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
|
5 | A0A0G2JZA1 (/IDA) A0A1W2Q6F3 (/IDA) F1M950 (/IDA) O55005 (/IDA) Q9QZI3 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
4 | Q9HCK4 (/IDA) Q9HCK4 (/IDA) Q9HCK4 (/IDA) Q9Y6N7 (/IDA) |
|
Axon guidance receptor activity GO:0008046
Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
|
3 | Q9HCK4 (/ISS) Q9HCK4 (/ISS) Q9HCK4 (/ISS) |
|
Axon guidance receptor activity GO:0008046
Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
|
3 | Q9HCK4 (/NAS) Q9HCK4 (/NAS) Q9HCK4 (/NAS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
3 | Q7TPD3 (/ISS) Q90Z70 (/ISS) Q9QZI3 (/ISS) |
|
Axon guidance receptor activity GO:0008046
Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
|
2 | O89026 (/ISO) Q7TPD3 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | O89026 (/ISO) Q7TPD3 (/ISO) |
|
Axon guidance receptor activity GO:0008046
Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
|
1 | Q9Y6N7 (/TAS) |
|
LRR domain binding GO:0030275
Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein.
|
1 | Q9Y6N7 (/IPI) |
Showing 1 to 10 of 11 entries
There are 118 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
17 |
A0A2R8QRK0 (/IMP)
A4JYD2 (/IMP)
A4JYD3 (/IMP)
A4JYH1 (/IMP)
A8DZ85 (/IMP)
B3DJN8 (/IMP)
F1QBD4 (/IMP)
F1QFK4 (/IMP)
F1R2D2 (/IMP)
O89026 (/IMP)
(7 more) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
12 |
A0A2R8QRK0 (/IGI)
A4JYD2 (/IGI)
A4JYD3 (/IGI)
A8DZ85 (/IGI)
B3DJN8 (/IGI)
F1QFK4 (/IGI)
F1R2D2 (/IGI)
O89026 (/IGI)
Q90Z69 (/IGI)
Q98SW3 (/IGI)
(2 more) |
|
Axon midline choice point recognition GO:0016199
The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
|
8 | A0A2R8QRK0 (/IMP) A4JYD3 (/IMP) A8DZ85 (/IMP) D3Z4M6 (/IMP) F1QFK4 (/IMP) Q90Z69 (/IMP) Q98SW3 (/IMP) Q9Z2I4 (/IMP) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
7 | A0A0G2JZA1 (/IEP) A0A1W2Q6F3 (/IEP) F1M950 (/IEP) Q9HCK4 (/IEP) Q9HCK4 (/IEP) Q9HCK4 (/IEP) Q9QZI3 (/IEP) |
|
Commissural neuron axon guidance GO:0071679
The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.
|
7 | A0A2R8QRK0 (/IMP) A4JYD3 (/IMP) A8DZ85 (/IMP) D3Z4M6 (/IMP) F1QFK4 (/IMP) Q90Z69 (/IMP) Q98SW3 (/IMP) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
6 | A0A0G2JZA1 (/IDA) A0A1W2Q6F3 (/IDA) F1M950 (/IDA) O55005 (/IDA) Q9QZI3 (/IDA) Q9Z2I4 (/IDA) |
|
Determination of ventral identity GO:0048264
The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
|
6 | A0A2R8QRK0 (/IMP) A4JYD3 (/IMP) A8DZ85 (/IMP) F1QFK4 (/IMP) Q90Z69 (/IMP) Q98SW3 (/IMP) |
|
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
|
6 | A0A2R8QRK0 (/IMP) A4JYD3 (/IMP) A8DZ85 (/IMP) F1QFK4 (/IMP) Q90Z69 (/IMP) Q98SW3 (/IMP) |
|
Metanephros development GO:0001656
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
5 | Q90Z70 (/ISS) Q9HCK4 (/ISS) Q9HCK4 (/ISS) Q9HCK4 (/ISS) Q9QZI3 (/ISS) |
|
Axon midline choice point recognition GO:0016199
The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
|
5 | A4JYH1 (/IGI) F1QBD4 (/IGI) O89026 (/IGI) Q7TPD3 (/IGI) Q90Z70 (/IGI) |
Showing 1 to 10 of 118 entries
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
11 |
A0A0G2JZA1 (/TAS)
D3Z4M6 (/TAS)
O55005 (/TAS)
O89026 (/TAS)
Q7TPD3 (/TAS)
Q96MS0 (/TAS)
Q9HCK4 (/TAS)
Q9HCK4 (/TAS)
Q9HCK4 (/TAS)
Q9Y6N7 (/TAS)
(1 more) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | A0A2R8QRK0 (/IDA) A4JYD3 (/IDA) A8DZ85 (/IDA) F1QFK4 (/IDA) Q90Z69 (/IDA) Q98SW3 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | A0A087WTM1 (/IDA) A0A087WZ85 (/IDA) A0A0A0MSX4 (/IDA) Q9Y6N7 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
4 | Q9HCK4 (/IDA) Q9HCK4 (/IDA) Q9HCK4 (/IDA) Q9Y6N7 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | Q7TPD3 (/ISS) Q90Z70 (/ISS) Q9QZI3 (/ISS) |
|
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
|
3 | Q9HCK4 (/ISS) Q9HCK4 (/ISS) Q9HCK4 (/ISS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
3 | Q9HCK4 (/HDA) Q9HCK4 (/HDA) Q9HCK4 (/HDA) |
|
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
2 | A0A024B7I3 (/IDA) F1NR30 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | O89026 (/ISO) Q7TPD3 (/ISO) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
2 | O55005 (/IDA) Q9Z2I4 (/IDA) |
Showing 1 to 10 of 19 entries
