The clustering and aggregation of membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes.

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.

A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.

Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.

Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.

The attachment of a cell to a cell of a different type via adhesion molecules.

The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

Any process that modulates the frequency, rate or extent of T cell differentiation.

The movement of a leukocyte within or between different tissues and organs of the body.

The attachment of one cell to another cell via adhesion molecules.

Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion.

Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.

The external part of the cell wall and/or plasma membrane.