The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.

The regulated release of interferon-gamma from a cell.

Any process that activates or increases the rate or extent of activated T cell proliferation.

Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.

Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Any process that activates or increases the rate or extent of T cell proliferation.

Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.

Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.

The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.

The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.

Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.

Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.

Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.

A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).

A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

The multiplication or reproduction of cells, resulting in the expansion of a cell population.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.

Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.

The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.

The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.

Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.

Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.

Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.

Any process that activates or increases the frequency, rate or extent of natural killer cell activation.

Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.

Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.

Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.

Any process that contributes to cytokine production by a T-helper 1 cell.

The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.

Any process that activates or increases the rate or extent of T cell proliferation.

Any process that activates or increases the rate or extent of activated T cell proliferation.

Any process that activates or increases the rate or extent of activated T cell proliferation.

Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.

Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.

Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.

Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.

Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.

Any process that activates or increases the frequency, rate or extent of cell adhesion.

Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.

Any process that activates or increases the rate or extent of lymphocyte proliferation.

Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.

Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.

Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.

Reactions triggered in response to the presence of a virus that act to protect the cell or organism.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.

Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.

Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.

Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.

Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.

A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.

Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.

The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.

A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.

The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.

Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.

Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.

Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.

Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.

Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.

Any process that activates or increases the frequency, rate or extent of natural killer cell activation.

Any process that activates or increases the frequency, rate or extent of natural killer cell activation.

Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.

Any process that activates or increases the frequency, rate, or extent of tissue remodeling.

Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.

A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.

An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.

The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.

The chemical reactions and pathways resulting in the formation of interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.

The chemical reactions and pathways resulting in the formation of interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.

Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.

Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.

Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.

Any process that activates or increases the frequency, rate or extent of cell adhesion.

Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.

Any process that activates or increases the rate or extent of lymphocyte proliferation.

Any process that activates or increases the frequency, rate or extent of the inflammatory response.

Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.

Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.

Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.

Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.

Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.

Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.

Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

The volume enclosed by the membranes of the endoplasmic reticulum.

A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.

The external part of the cell wall and/or plasma membrane.

The volume enclosed by the membrane of an endosome.

A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.

A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.

A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

The volume enclosed by the membrane of a late endosome.