The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"HesB-like domain
".
FunFam 1: Iron-binding protein IscA
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
186 |
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
P0AAC8 (/IPI)
(176 more) |
|
2 iron, 2 sulfur cluster binding GO:0051537
Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
186 |
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
(176 more) |
|
Ferrous iron binding GO:0008198
Interacting selectively and non-covalently with ferrous iron, Fe(II).
|
185 |
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
(175 more) |
|
Iron chaperone activity GO:0034986
Directly binding to and delivering iron ions to a target protein.
|
185 |
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
(175 more) |
|
Iron chaperone activity GO:0034986
Directly binding to and delivering iron ions to a target protein.
|
185 |
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
(175 more) |
|
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
|
6 | B7J5X1 (/IDA) B7J5X1 (/IDA) B7J5X1 (/IDA) B7J5X1 (/IDA) Q07821 (/IDA) Q07821 (/IDA) |
|
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
|
2 | Q07821 (/ISA) Q07821 (/ISA) |
|
Iron-sulfur transferase activity GO:0036455
Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).
|
1 | P78859 (/IDA) |
|
Iron-sulfur cluster binding GO:0051536
Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
|
1 | P78859 (/IDA) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
|
187 |
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
P0AAC8 (/IMP)
(177 more) |
|
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
|
185 |
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
(175 more) |
|
Small molecule metabolic process GO:0044281
The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
|
14 |
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
(4 more) |
|
Response to magnetism GO:0071000
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.
|
3 | Q8T3X9 (/IDA) Q8T3X9 (/IDA) Q8T3X9 (/IDA) |
|
Biotin biosynthetic process GO:0009102
The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
|
2 | Q07821 (/IGI) Q07821 (/IGI) |
|
Biotin biosynthetic process GO:0009102
The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
|
2 | Q07821 (/IMP) Q07821 (/IMP) |
|
Iron-sulfur cluster assembly GO:0016226
The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
|
2 | Q07821 (/IGI) Q07821 (/IGI) |
|
Protein maturation by iron-sulfur cluster transfer GO:0097428
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
|
2 | Q07821 (/IMP) Q07821 (/IMP) |
|
Protein maturation by [4Fe-4S] cluster transfer GO:0106035
The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
|
2 | Q07821 (/IMP) Q07821 (/IMP) |
|
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
|
1 | Q4QRC6 (/IMP) |
|
[4Fe-4S] cluster assembly GO:0044572
The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.
|
1 | P78859 (/ISS) |
|
Endocrine process GO:0050886
The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.
|
1 | Q80W96 (/NAS) |
|
Protein maturation by iron-sulfur cluster transfer GO:0097428
The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
|
1 | P78859 (/IDA) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
185 |
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
P0AAC8 (/IDA)
(175 more) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
14 |
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
Q9BUE6 (/TAS)
(4 more) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | I3ITR1 (/HDA) P78859 (/HDA) Q9D924 (/HDA) |
|
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
|
2 | Q07821 (/IDA) Q07821 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | P78859 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q54VS1 (/ISS) |
