The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: CD40 ligand

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
CD40 receptor binding GO:0005174
Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
CD40 receptor binding GO:0005174
Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes.
2 P29965 (/IPI) Q9Z2V2 (/IPI)
CD40 receptor binding GO:0005174
Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes.
2 P27548 (/ISO) P27548 (/ISO)
CD40 receptor binding GO:0005174
Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes.
1 B8YI05 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P29965 (/IPI)
Showing 1 to 5 of 5 entries

There are 63 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
Activation of JUN kinase activity GO:0007257
The initiation of the activity of the inactive enzyme JUN kinase (JNK).
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
Platelet activation GO:0030168
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
Positive regulation of interleukin-4 production GO:0032753
Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
B cell proliferation GO:0042100
The expansion of a B cell population by cell division. Follows B cell activation.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
27 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(17 more)
Positive regulation of interleukin-10 production GO:0032733
Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.
26 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P27548 (/ISS) P27548 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(16 more)
Positive regulation of immune response to tumor cell GO:0002839
Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
2 P27548 (/ISO) P27548 (/ISO)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
2 P27548 (/ISO) P27548 (/ISO)
Showing 1 to 10 of 63 entries

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
24 O97605 (/ISS) O97626 (/ISS) O97626 (/ISS) P51749 (/ISS) P51749 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS) P63304 (/ISS)
(14 more)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
3 B8YI05 (/IDA) P27548 (/IDA) P27548 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P27548 (/ISO) P27548 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P29965 (/IDA) Q9Z2V2 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P27548 (/ISO) P27548 (/ISO)
Cell projection GO:0042995
A prolongation or process extending from a cell, e.g. a flagellum or axon.
2 P27548 (/ISO) P27548 (/ISO)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
2 P27548 (/ISO) P27548 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9Z2V2 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P29965 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P29965 (/TAS)
Showing 1 to 10 of 13 entries
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