The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Jelly Rolls
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1193
3D
4r8hB01 - 79.5
3
985
3D
3mzhB01 - 97.9
2
968 - - 91.7
4
869
3D
5e44A01 - 92.6
6
649
3D
5kjzA00 - 91.9
5
648
3D
2eteB00 - 96.0
7
638
3D
3u0zB02 - 72.7
9
574
3D
4lloG00 - 74.0
8
GEF
569 - - 25.6
10
565 - - 92.5
11
526 - - 80.6
12
506 - - 96.1
13
465
3D
4dinB01 - 76.6
14
Eag-related
418
3D
3ukvC02 - 76.0
15
401
3D
4mh0E02 - 49.0
16
380
3D
2oyzA00 - 91.0
17
370
3D
4x6qB01 - 87.3
18
353
3D
1xruB02 - 80.6
19
321
3D
2d93A00 - 44.7
20
304 - - 89.4
21
297
3D
1tq5A02 - 57.6
22
293 - - 84.2
23
287
3D
5nw7A02 - 85.6
24
262
3D
1wgpA01 - 79.8
25
254 - - 97.3
26
244 - - 65.1
27
236
3D
4jvaA02 - 73.2
28
221 - - 24.6
30
215
3D
5zvxA02 - 96.8
29
214 - - 20.1
31
191
3D
4qgnA00 - 83.9
35
184
3D
4z07E00 - 81.5
45
181
3D
2q4sA00 - 82.5
37
179
3D
5jd7A00 - 68.1
32
178 - - 93.3
33
176
3D
2vpvB00 - 98.9
34
171 - - 90.9
36
167 - - 59.3
42
157
3D
5opcA01 - 90.1
38
141
3D
6bq8A00 - 88.3
39
127
3D
3of1A01 - 94.0
43
124
3D
5c8wF00 - 81.5
40
121 - - 63.9
73
121
3D
1ud1C02 - 97.3
41
120 - - 9.9
44
116 - - 95.9
51
112
3D
1dztB00 - 73.3
46
112 - - 73.0
47
108 - - 94.0
48
106 - - 72.7
49
104 - - 14.7
50
103 - - 3.4
54
100
3D
3la7B01 - 47.2
52
99
3D
4f7zA01 - 31.3
53
96 - - 68.7
56
93
3D
4qgmA00 - 83.2
57
92
3D
4d7tB02 - 98.2
55
92 - - 83.2
58
86 - - 28.1
59
85 - - 87.3
61
84 - - 64.5
62
84 - - 83.6
60
84 - - 72.2
63
80 - - 61.8
64
77 - - 88.4
65
71 - - 11.4
66
69 - - 9.7
68
69
3D
5e16A00 - 95.6
67
68 - - 93.4
69
67 - - 47.6
70
66 - - 74.7
72
65 - - 84.7
71
65 - - 6.4
81
63
3D
6h1iA01 - 72.2
77
61
3D
5tkqA00 - 90.4
74
60 - - 99.0
80
60
3D
1lrhD00 - 74.3
75
59 - - 31.3
76
58 - - 25.9
78
54 - - 78.8
79
53 - - 83.0
137
S
52
3D
4e2sP00 - 41.5
82
50 - - 12.1
84
S
49
3D
1rc6B00 - 8.8
83
49 - - 95.3
124
48
3D
1ud1C01 - 92.0
162
47
3D
1caxF00 - 80.1
85
47 - - 11.5
86
47 - - 84.7
87
46 - - 0.0
88
46 - - 53.1
89
45 - - 95.2
91
45
3D
4ofgA00 - 24.4
93
44
3D
1zvfB01 - 80.3
90
44 - - 73.1
92
43 - - 24.2
94
42 - - 17.9
95
41 - - 2.6
96
40 - - 38.8
100
40
3D
3iwzD01 - 7.9
181
39
3D
1uikC01 - 73.9
98
38 - - 86.7
97
38 - - 46.7
212
38
3D
5x6eN01 - 0.0
99
37 - - 92.8
101
36 - - 7.3
382
S
36
3D
4j1xC02 - 48.8
104
32 - - 77.5
103
32 - - 6.7
105
32 - - 50.7
102
32 - - 70.3
106
30 - - 15.1
107
27 - - 88.5
113
27
3D
2qvsB02 - 39.4
108
27 - - 80.3
109
26 - - 85.3
118
26
3D
3of1A02 - 88.1
110
26 - - 9.7
112
26 - - 18.0
111
26 - - 88.7
117
25 - - 45.6
114
25 - - 12.4
129
25
3D
4i2oB01 - 76.1
116
25 - - 9.5
115
25 - - 13.7
119
24 - - 22.5
123
24 - - 97.3
121
24 - - 2.6
120
24 - - 82.3
122
24 - - 90.6
139
24
3D
3h7yB02 - 9.3
127
23 - - 25.5
130
23 - - 80.0
126
23 - - 3.6
128
23 - - 3.5
125
23 - - 23.9
133
22 - - 41.0
165
22
3D
2ixcD00 - 56.4
131
22 - - 75.0
132
22 - - 9.0
135
21 - - 71.8
134
21 - - 5.3
142
putative
20 - - 79.7
140
20 - - 8.4
141
20 - - 86.2
138
20 - - 16.0
136
20 - - 63.2
145
19 - - 73.4
157
19
3D
2zcwA01 - 77.8
146
19 - - 73.7
143
19 - - 2.0
156
19
3D
5kbfB01 - 2.8
144
19 - - 45.3
148
18 - - 85.7
147
2OG II
18 - - 65.6
154
17 - - 81.4
153
Crp/Fnr family
17 - - 14.2
149
17 - - 72.1
151
17 - - 15.5
150
17 - - 88.8
158
17 - - 5.6
155
17 - - 7.2
152
17 - - 17.2
160
16 - - 0.0
163
16 - - 9.4
161
16 - - 0.0
159
16 - - 34.1
164
16 - - 23.5
274
15
3D
3bu7B00 - 90.5
168
15 - - 27.7
228
15
3D
4avcB01 - 34.9
166
15 - - 60.4
172
15 - - 36.0
170
15 - - 19.8
171
15 - - 17.4
173
15 - - 71.7
169
Catabolite gene activator
15 - - 16.0
167
15 - - 3.9
175
14 - - 19.4
178
14 - - 12.5
176
14 - - 11.9
174
14 - - 63.8
177
14 - - 11.8
183
13 - - 10.6
185
13 - - 10.3
182
13 - - 1.4
180
13 - - 9.6
186
13 - - 27.9
179
13 - - 2.3
184
13 - - 36.0
194
12 - - 16.6
197
12 - - 71.5
516
12
3D
4tlfD02 - 0.8
188
12 - - 44.2
191
12 - - 14.5
193
12 - - 54.6
187
12 - - 56.8
192
12 - - 88.1
195
12 - - 0.0
189
12 - - 71.1
190
12 - - 0.0
196
12 - - 10.1
202
11 - - 6.3
200
11 - - 11.0
199
11 - - 11.8
201
11 - - 0.0
203
11 - - 9.8
204
11 - - 0.0
198
11 - - 42.7
220
10 - - 92.4
213
MCD
10 - - 14.8
205
10 - - 76.8
208
10 - - 13.2
211
10 - - 32.1
206
10 - - 65.4
218
10 - - 2.8
210
10 - - 17.5
216
10 - - 79.8
284
10
3D
1vp6C00 - 21.7
215
10 - - 47.3
209
10 - - 0.0
217
10 - - 0.0
214
10 - - 39.1
268
10
3D
2z69C00 - 4.2
219
10 - - 0.0
207
10 - - 83.6
304
10
3D
2xlgA00 - 39.8
226
9 - - 10.6
225
9 - - 77.1
222
9 - - 81.5
223
9 - - 7.7
234
9 - - 0.0
221
9 - - 8.6
391
9
3D
1j3rB00 - 8.3
230
9 - - 41.8
229
9 - - 7.6
235
9 - - 18.2
232
9 - - 1.6
233
9 - - 0.0
227
9 - - 2.2
224
9 - - 46.4
231
9 - - 12.4
250
8 - - 25.6
244
8 - - 72.4
239
8 - - 9.2
252
8 - - 67.5
247
8 - - 17.9
253
8 - - 90.2
237
8 - - 67.3
249
8 - - 93.8
251
8 - - 66.1
238
8 - - 15.6
241
8 - - 9.7
236
8 - - 17.5
263
8
3D
1zybA01 - 10.2
243
8 - - 51.4
245
8 - - 38.9
242
8 - - 35.4
246
8 - - 88.8
240
8 - - 5.5
248
8 - - 3.4
267
7 - - 71.0
256
7 - - 5.5
258
7 - - 10.6
255
7 - - 27.1
264
7 - - 0.0
409
7
3D
4yarA03 - 12.1
269
7 - - 2.0
271
7 - - 1.3
273
7 - - 79.7
259
7 - - 15.7
261
7 - - 22.5
257
7 - - 0.9
266
7 - - 0.0
260
7 - - 0.0
272
7 - - 0.0
262
7 - - 12.2
270
7 - - 0.0
254
7 - - 8.4
265
7 - - 0.0
295
6 - - 0.0
300
6 - - 40.9
292
6 - - 22.1
289
6 - - 84.0
296
6 - - 0.0
290
6 - - 43.0
277
6 - - 10.1
298
6 - - 21.7
291
6 - - 5.8
279
6 - - 12.2
293
6 - - 0.9
301
6 - - 37.3
287
6 - - 7.0
282
6 - - 0.0
285
6 - - 8.6
299
6 - - 77.6
286
6 - - 18.4
280
6 - - 5.7
288
6 - - 12.7
281
6 - - 0.9
275
6 - - 18.4
294
6 - - 0.0
278
6 - - 7.6
283
6 - - 86.7
276
6 - - 21.7
297
6 - - 0.0
311
5 - - 47.3
306
5 - - 45.5
325
5 - - 3.9
322
5 - - 14.3
308
5 - - 0.0
328
5 - - 0.0
302
5 - - 70.7
313
5 - - 22.2
305
5 - - 62.3
326
5 - - 11.2
320
5 - - 42.9
315
5 - - 12.5
303
5 - - 14.6
312
5 - - 70.1
321
5 - - 67.6
334
5 - - 50.5
310
5 - - 0.0
316
5 - - 0.0
318
5 - - 35.9
323
5 - - 8.2
337
5 - - 53.8
329
5 - - 1.3
335
5 - - 73.8
332
5 - - 61.8
314
5 - - 14.7
336
5 - - 18.4
330
5 - - 6.6
317
5 - - 9.4
309
5 - - 0.0
331
5 - - 0.0
324
5 - - 0.0
397
5
3D
1o4tB00 - 0.0
307
5 - - 14.7
319
5 - - 46.1
333
5 - - 77.6
327
5 - - 1.9
347
4 - - 12.5
352
4 - - 3.0
339
4 - - 6.3
355
4 - - 30.6
364
4 - - 8.1
377
4 - - 72.4
344
4 - - 48.8
358
4 - - 16.9
374
4 - - 0.0
367
4 - - 11.6
350
4 - - 12.2
356
4 - - 8.4
351
4 - - 9.3
369
4 - - 11.8
349
4 - - 14.4
587
4
3D
3b02A01 - 1.1
379
4 - - 78.5
353
4 - - 7.0
359
4 - - 60.0
373
4 - - 6.8
361
4 - - 6.7
585
4
3D
1ft9B01 - 0.0
343
4 - - 36.3
380
4 - - 85.9
371
4 - - 9.4
363
4 - - 7.0
338
4 - - 47.4
341
4 - - 16.8
370
4 - - 8.3
376
4 - - 64.3
348
4 - - 0.0
362
4 - - 0.8
354
4 - - 49.5
365
4 - - 2.9
346
4 - - 2.4
340
4 - - 0.0
378
4 - - 80.6
375
4 - - 35.1
357
4 - - 10.2
372
4 - - 1.9
366
4 - - 0.0
360
4 - - 72.4
345
4 - - 66.0
381
4 - - 75.0
368
4 - - 5.5
342
4 - - 34.3
398
3 - - 0.0
427
3 - - 13.8
433
3 - - 6.8
396
3 - - 7.6
390
3 - - 7.3
404
3 - - 21.0
442
3 - - 60.4
424
3 - - 11.1
431
3 - - 14.0
389
3 - - 78.5
395
3 - - 0.0
419
3 - - 5.6
440
3 - - 71.1
407
3 - - 15.8
392
3 - - 4.4
430
3 - - 1.8
436
3 - - 0.0
387
3 - - 24.1
441
3 - - 45.4
438
3 - - 20.7
393
3 - - 0.0
417
3S
3 - - 9.0
435
3 - - 0.0
429
3 - - 7.1
384
3 - - 10.8
432
3 - - 4.7
414
3 - - 38.8
443
3 - - 69.3
416
3 - - 72.7
410
3 - - 3.9
388
3 - - 48.2
401
3 - - 0.0
418
3 - - 0.8
437
3 - - 60.0
386
3 - - 5.4
423
3 - - 0.6
399
3 - - 0.0
403
3 - - 32.4
415
3 - - 71.5
412
3 - - 64.1
434
3 - - 0.0
421
3S
3 - - 13.4
385
3 - - 12.1
402
3 - - 0.0
444
3 - - 16.3
428
3 - - 8.4
405
3 - - 8.9
413
3 - - 40.6
383
3 - - 43.0
420
3 - - 2.5
426
3 - - 11.9
394
3 - - 0.0
411
3 - - 0.0
400
3 - - 2.9
406
3 - - 6.0
425
3 - - 8.3
439
3 - - 41.1
408
3 - - 4.5
422
3 - - 0.0
558
2 - - 0.0
457
2 - - 0.0
589
2 - - 0.0
513
2 - - 7.4
505
2 - - 22.8
494
2 - - 6.6
475
2 - - 0.0
528
2 - - 6.6
502
2 - - 18.1
460
2 - - 43.2
466
2 - - 29.0
544
2 - - 26.9
472
2 - - 40.4
602
2 - - 45.2
592
2 - - 39.6
445
2 - - 20.2
556
2 - - 4.4
550
2 - - 14.5
595
2 - - 36.1
574
2 - - 0.0
567
2 - - 5.0
468
2 - - 34.6
520
2 - - 4.4
526
2 - - 0.0
481
2 - - 0.0
500
2 - - 0.0
462
2 - - 20.2
448
2 - - 0.0
547
2 - - 39.8
506
2 - - 14.1
476
2 - - 7.0
470
2 - - 38.4
465
2 - - 30.4
598
2 - - 42.3
497
2 - - 0.0
511
2 - - 12.7
454
2 - - 3.0
522
2 - - 0.0
555
2 - - 23.7
478
2 - - 0.0
564
2 - - 7.9
577
2 - - 0.0
508
2 - - 43.8
483
2 - - 5.1
446
2 - - 36.0
525
2 - - 9.4
539
2 - - 0.0
552
2 - - 23.1
600
2 - - 41.9
590
2 - - 36.1
596
2 - - 41.8
584
2 - - 0.0
463
2 - - 8.6
471
2 - - 39.8
499
2 - - 43.7
501
2 - - 45.2
510
2 - - 41.2
549
2 - - 43.1
523
2 - - 0.9
482
2 - - 0.0
537
2 - - 11.3
591
2 - - 39.6
553
2 - - 25.6
518
2 - - 0.0
601
2 - - 47.0
579
2 - - 0.0
485
2 - - 0.0
512
2 - - 6.0
515
2 - - 0.0
461
2 - - 20.9
473
2 - - 26.1
488
2 - - 0.0
503
2 - - 23.3
459
2 - - 22.6
551
2 - - 20.7
593
2 - - 40.7
603
2 - - 43.4
569
2 - - 0.0
480
2 - - 10.2
534
2 - - 0.0
486
2 - - 1.1
521
2 - - 10.0
449
2 - - 0.0
571
2 - - 0.0
599
2 - - 42.9
484
2 - - 0.0
530
2 - - 2.0
536
2 - - 8.7
563
2 - - 7.2
491
2 - - 0.0
509
2 - - 43.1
453
2 - - 1.2
517
2 - - 10.3
479
2 - - 9.6
582
2 - - 0.0
538
2 - - 0.0
541
2 - - 0.0
532
2 - - 1.8
573
2 - - 39.2
588
2 - - 0.0
559
2 - - 0.0
487
2 - - 0.0
561
2 - - 0.8
535
2 - - 0.0
529
2 - - 0.0
580
2 - - 0.0
586
2 - - 9.8
543
2 - - 29.5
469
2 - - 37.4
514
2 - - 0.0
451
2 - - 0.0
493
2 - - 7.9
560
2 - - 4.4
566
2 - - 1.1
572
2 - - 0.0
533
2 - - 2.0
527
2 - - 0.0
594
2 - - 37.8
575
2 - - 0.0
458
2 - - 9.5
557
2 - - 3.1
489
2 - - 4.3
581
2 - - 0.0
504
2 - - 20.0
495
2 - - 4.1
542
2 - - 30.0
474
2 - - 0.0
467
2 - - 16.8
568
2 - - 0.0
456
2 - - 12.2
450
2 - - 8.0
492
2 - - 0.0
545
2 - - 31.9
554
2 - - 22.1
565
2 - - 7.9
498
2 - - 0.8
597
2 - - 41.4
524
2 - - 9.3
531
2 - - 0.0
562
2 - - 6.3
548
2 - - 43.0
447
2 - - 0.0
576
2 - - 0.0
570
2 - - 5.9
490
2 - - 0.0
496
2 - - 8.6
452
2 - - 0.0
578
2 - - 0.0
464
2 - - 2.1
477
2 - - 0.0
519
2 - - 0.0
540
2 - - 11.4
583
2 - - 2.2
546
2 - - 40.2
507
2 - - 29.6
455
2 - - 0.7
626
1 - - 0.0
620
1 - - 0.0
703
1 - - 0.0
787
1 - - 0.0
715
1 - - 0.0
817
1 - - 0.0
674
1 - - 0.0
667
1 - - 0.0
809
1 - - 0.0
695
1 - - 0.0
650
1 - - 0.0
656
1 - - 0.0
712
1 - - 0.0
692
1 - - 0.0
644
1 - - 0.0
734
1 - - 0.0
721
1 - - 0.0
628
1 - - 0.0
769
1 - - 0.0
605
1 - - 0.0
689
1 - - 0.0
751
1 - - 0.0
793
1 - - 0.0
658
1 - - 0.0
836
1 - - 0.0
613
1 - - 0.0
830
1 - - 0.0
716
1 - - 0.0
710
1 - - 0.0
696
1 - - 0.0
749
1 - - 0.0
690
1 - - 0.0
639
1 - - 0.0
625
1 - - 0.0
652
1 - - 0.0
664
1 - - 0.0
677
1 - - 0.0
608
1 - - 0.0
814
1 - - 0.0
701
1 - - 0.0
784
1 - - 0.0
622
1 - - 0.0
655
1 - - 0.0
832
Crp/Fnr family
1 - - 0.0
791
1 - - 0.0
698
1 - - 0.0
753
1 - - 0.0
718
1 - - 0.0
611
1 - - 0.0
779
1 - - 0.0
829
1 - - 0.0
737
1 - - 0.0
835
1 - - 0.0
647
1 - - 0.0
606
1 - - 0.0
723
1 - - 0.0
691
1 - - 0.0
798
1 - - 0.0
653
1 - - 0.0
679
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804
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637
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623
1 - - 0.0
833
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610
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616
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790
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686
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629
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635
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1 - - 0.0
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1 - - 0.0
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661
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624
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1 - - 0.0
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