The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Acid Proteases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Aspartic proteinase A1reninPlasmepsin-2Vacuolar aspartic proteaseBasic 7S globulinLysosomal aspartic proteaseSC:2DNA damage inducible 1 homolog 2DNA damage-inducible proteinGag polyproteinProteaseSC:3Beta-secretase 1Putative xylanase inhibitorSC:4Basic 7S globulinGamma conglutin 1SC:5ReninPlasmepsin-2Lysosomal aspartic proteaseCathepsin D preproproteinSC:6Beta-secretase 1Gag-Pol polyproteinVacuolar aspartic proteinasePepsin ACathepsin ECathepsin DAspartyl protease family protein 2Aspartic proteaseAspartyl protease family protein 1Aspartyl protease AED1Aspartyl protease family protein 1Aspartyl protease family proteinProbable aspartic protease At2g35615Uncharacterized proteinAspartic proteinase-like protein 2aspartyl protease family protein 2Aspartic proteinase-like protein 2Aspartyl protease AED1Aspartyl protease AED3Aspartic proteaseEndothiapepsinAspartyl protease family proteinEndothiapepsinAspartic proteinase Asp1 isoform AEukaryotic aspartyl protease family proteinAspartyl protease family proteinEukaryotic aspartyl protease family proteinAspartyl protease AED1Aspartyl protease family proteinAspartyl protease family proteinCathepsin D preproproteinaspartyl protease AED3Cathepsin Dretroviral-like aspartic protease 1 isoform X3Aspartic proteinase PCS1Napsin A aspartic peptidaseAspartyl protease AED1Aspartic proteinase CDR1Putative aspartic proteaseASpartyl ProteaseEukaryotic aspartyl protease family proteinretrotransposon-derived protein PEG10 isoform 1Probable aspartyl protease At4g16563Eukaryotic aspartyl protease family proteinEukaryotic aspartyl protease family proteinASpartyl ProteaseNapsin A aspartic peptidaseAspartic-type endopeptidase ctsDAspartyl protease APCB1ASpartyl Proteaseaspartic proteinase nepenthesin-1Eukaryotic aspartyl protease family proteinEukaryotic aspartyl protease family proteinNapsin A aspartic peptidaseEndopeptidase, putativeAspartic-type endopeptidase (OpsB)Eukaryotic aspartyl protease family proteinAspartyl protease family proteinAspartic proteinase PCS1Aspartic proteinase PCS1Os05g0384300 proteinUncharacterized proteinAspartic proteinase nepenthesin-2Eukaryotic aspartyl protease family proteinPutative aspartic proteinase nepenthesin IIPlasmepsin VPlasmepsin XPlasmepsin Xlysosomal aspartic proteaseUncharacterized proteinAspartic-type endopeptidase (CtsD), putativeASpartyl ProteaseGag-Pol polyproteinEukaryotic aspartyl protease family proteinUncharacterized proteinAspartyl protease family proteinGG22202Aspartic endopeptidase (AP1)Plasmepsin 5Eukaryotic aspartyl protease family proteinAspartyl protease family proteinBasic 7S globulinAspartyl protease AED3Chloroplast nucleoid DNA-binding protein-likePutative aspartyl proteaseCathepsin E-like proteaseUncharacterized proteinYALI0C10923pAspartyl protease familyUncharacterized proteinaspartic proteinase PCS1Plasmepsin VIIPepsin-like aspartic protease A1Putative aspartyl proteaseEukaryotic aspartyl protease family proteinYps7pPlasmepsin IXPlasmepsin IXLysosomal aspartic proteaseEndopeptidase, putativeCathepsin DOs01g0937500 proteinEukaryotic aspartyl protease family proteinEukaryotic aspartyl protease family proteinAspartic proteinase nepenthesin-2Eukaryotic aspartyl protease family proteinPlasmepsin VIIPolyproteinTransposon Tf2-8 polyproteinEukaryotic aspartyl protease family protein, expressedOs04g0334700 proteinPlasmepsin IXAspartic proteinase A1Retrovirus-related Pol polyprotein from transposon opus-like ProteinUncharacterized proteinUncharacterized proteinCathepsin E-like proteaseYALI0D22957pPeptidase, putativePutative nucleoid DNA-binding protein cnd41, chloroplastEukaryotic aspartyl protease family proteinAspartic protease 3S5Os01g0696800 proteinUncharacterized proteinOs01g0937800 proteinOSJNBa0006A01.20 proteinAspartic proteaseAspartic proteaseAspartic proteaseGPI-anchored aspartic proteaseUncharacterized proteinUncharacterized proteinGag-Pro polyproteinBasic 7S globulinAspartic proteinase nepenthesin-2Eukaryotic aspartyl protease family proteinUncharacterized proteinPlasmepsin VIOSJNba0093F12.2 proteinEukaryotic aspartyl protease family protein, expressedASpartyl ProteaseYALI0B06303pAspartic proteinase nepenthesin-1cDNA FLJ60006, highly similar to Pepsin AUncharacterized proteinTransposon Tf2-9 polyprotein-like ProteinEukaryotic aspartyl protease family proteinUncharacterized proteinEukaryotic aspartyl protease family protein, expressedUncharacterized proteinEukaryotic aspartyl protease family proteinEukaryotic aspartyl protease family proteinASpartyl ProteaseUncharacterized proteinUncharacterized proteinEukaryotic aspartyl protease family proteinProtein CBG28002Protein CBG08575Protein CBG08575ASpartyl ProteaseAspartyl protease AED1Acid extracellular proteaseBeta-secretase 1Plasmepsin VIIIPeptidase, putativePlasmepsin VIIIOs06g0119600 proteinAspartic-type endopeptidase, putativeSap99pUncharacterized proteinUncharacterized proteinUncharacterized proteinPol polyproteinPro-Pol polyproteinUncharacterized proteinAspartic peptidase domain-containing proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinWGS project CABT00000000 data, contig 2.21Uncharacterized proteinUncharacterized proteinPredicted proteinYALI0D02024pUncharacterized proteinAcid proteaseOs08g0207800 proteinAcid proteasePlasmepsin VIEndopeptidaseOs09g0428200 proteinEndopeptidaseOs09g0556100 proteinUncharacterized proteinPepsin-type aspartyl proteaseAspartyl protease family protein 2Uncharacterized proteinChromosome 16, whole genome shotgun sequenceUncharacterized proteinUncharacterized proteinASpartyl ProteaseAspartic proteinase NANA, chloroplastUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinASpartyl ProteaseSap98pAcid proteaseAcid proteaseEndopeptidaseGD19153FI01813pAcid proteaseOs08g0207800 proteinRelated to aspartyl proteinase SAP3Acid proteaseAcid proteaseAcid proteaseSecreted aspartic proteinaseUncharacterized proteinNuclear receptor interacting protein 2Pepsin AUncharacterized proteinUncharacterized proteinUncharacterized proteinProbable aspartic-type endopeptidase AFUA_3G01220Aspartic proteinase nepenthesin-2ASpartyl ProteaseASpartyl ProteaseReninUncharacterized proteinAspartic proteinase nepenthesin-1Pepsin AAspartic peptidase domain-containing proteinAspartyl protease family proteinAspartic peptidase domain-containing proteinAspartic peptidase domain-containing proteinUncharacterized proteinUncharacterized proteinGD19154Putative aspartic endopeptidaseAspartic peptidase domain-containing proteinPutative aspartic endopeptidaseEukaryotic aspartyl protease family proteinAspartic peptidase domain-containing proteinPepsin AAspartic peptidase domain-containing proteinAspartyl protease, putativeSecretory aspartyl protease, putativeEukaryotic aspartyl protease family proteinPepsin AUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinAspartic peptidase domain-containing protein
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FunFam 149: Uncharacterized protein

There are 0 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

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