The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: Amyloid beta A4 protein-binding family A member 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 B2RUJ5 (/IPI) O17583 (/IPI) O35430 (/IPI) O35431 (/IPI) P98084 (/IPI) Q02410 (/IPI) Q99767 (/IPI) Q9GQQ6 (/IPI) Q9VX41 (/IPI) Q9W2S5 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
5 E1JJN6 (/IPI) M9PF12 (/IPI) Q9GQQ6 (/IPI) Q9VX41 (/IPI) X2JE74 (/IPI)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
2 O35430 (/IPI) O35431 (/IPI)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
2 B2RUJ5 (/ISO) P98084 (/ISO)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
1 O35430 (/IDA)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
1 B2RUJ5 (/ISO)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
1 O35431 (/NAS)
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
1 O17583 (/IPI)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 O35430 (/IPI)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 B2RUJ5 (/ISO)
Showing 1 to 10 of 14 entries

There are 34 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein localization to membrane GO:0072657
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
9 E1JJN6 (/IMP) M9PF12 (/IMP) M9PGU7 (/IMP) Q5BI79 (/IMP) Q9GQQ6 (/IMP) Q9VX41 (/IMP) Q9W2S5 (/IMP) X2JB44 (/IMP) X2JE74 (/IMP)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
5 E1JJN6 (/NAS) M9PF12 (/NAS) Q9GQQ6 (/NAS) Q9VX41 (/NAS) X2JE74 (/NAS)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
5 E1JJN6 (/NAS) M9PF12 (/NAS) Q9GQQ6 (/NAS) Q9VX41 (/NAS) X2JE74 (/NAS)
Synaptic vesicle targeting GO:0016080
The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
5 E1JJN6 (/NAS) M9PF12 (/NAS) Q9GQQ6 (/NAS) Q9VX41 (/NAS) X2JE74 (/NAS)
Synaptic vesicle docking GO:0016081
The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
5 E1JJN6 (/NAS) M9PF12 (/NAS) Q9GQQ6 (/NAS) Q9VX41 (/NAS) X2JE74 (/NAS)
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
5 E1JJN6 (/IMP) M9PF12 (/IMP) Q9GQQ6 (/IMP) Q9VX41 (/IMP) X2JE74 (/IMP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
2 B2RUJ5 (/IGI) P98084 (/IGI)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 B2RUJ5 (/IGI) P98084 (/IGI)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
2 Q02410 (/TAS) Q99767 (/TAS)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
2 B2RUJ5 (/IGI) P98084 (/IGI)
Showing 1 to 10 of 34 entries

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 E1JJN6 (/IDA) M9PF12 (/IDA) O17583 (/IDA) Q9GQQ6 (/IDA) Q9VX41 (/IDA) X2JE74 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O35430 (/TAS) O35431 (/TAS) Q02410 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 O17583 (/IDA) O35430 (/IDA) O35431 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 O17583 (/IDA) Q02410 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 B2RUJ5 (/ISO) P98084 (/ISO)
Schaffer collateral - CA1 synapse GO:0098685
A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.
2 B2RUJ5 (/IMP) P98084 (/IMP)
Golgi trans cisterna GO:0000138
The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.
1 O17583 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
1 B2RUJ5 (/ISO)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
1 Q02410 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 B2RUJ5 (/IDA)
Showing 1 to 10 of 22 entries
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