The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Phosphoenolpyruvate Carboxykinase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Phosphoenolpyruvate carboxykinase (ATP)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phosphoenolpyruvate carboxykinase (ATP) activity GO:0004612
Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.
96 P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P22259 (/IDA)
(86 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
87 P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA)
(77 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
87 P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA) P22259 (/IDA)
(77 more)
Phosphoenolpyruvate carboxykinase (ATP) activity GO:0004612
Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.
27 Q81KH8 (/ISS) Q81KH8 (/ISS) Q81KH8 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS)
(17 more)
Phosphoenolpyruvate carboxykinase (ATP) activity GO:0004612
Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.
11 P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) P10963 (/IMP) Q9T074 (/IMP)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P10963 (/IPI) P10963 (/IPI) P10963 (/IPI) P10963 (/IPI) P10963 (/IPI) P10963 (/IPI) P10963 (/IPI) P10963 (/IPI) P10963 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 Q81KH8 (/ISS) Q81KH8 (/ISS) Q81KH8 (/ISS)
Phosphoenolpyruvate carboxykinase (ATP) activity GO:0004612
Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.
1 Q96UL8 (/RCA)
Phosphoenolpyruvate carboxykinase (GTP) activity GO:0004613
Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.
1 Q96UL8 (/RCA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
87 P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP) P22259 (/IMP)
(77 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
87 P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS) P22259 (/TAS)
(77 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
27 Q81KH8 (/ISS) Q81KH8 (/ISS) Q81KH8 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS) Q8IDR1 (/ISS)
(17 more)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
9 P10963 (/IEP) P10963 (/IEP) P10963 (/IEP) P10963 (/IEP) P10963 (/IEP) P10963 (/IEP) P10963 (/IEP) P10963 (/IEP) P10963 (/IEP)
Defense response to fungus, incompatible interaction GO:0009817
A response of an organism to a fungus that prevents the occurrence or spread of disease.
2 Q9T074 (/IDA) Q9T074 (/IDA)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
2 Q9T074 (/IEP) Q9T074 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
2 Q9T074 (/IEP) Q9T074 (/IEP)
Acetate metabolic process GO:0006083
The chemical reactions and pathways involving acetate, the anion of acetic acid.
1 Q96UL8 (/IEP)
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
1 Q96UL8 (/RCA)
Glycolytic process GO:0006096
The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
1 Q96UL8 (/RCA)
Carbon utilization GO:0015976
A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
1 Q96UL8 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
98 P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P10963 (/IDA) P22259 (/IDA)
(88 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9T074 (/IDA) Q9T074 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
2 Q9T074 (/IDA) Q9T074 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q9T074 (/IDA) Q9T074 (/IDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q75JD5 (/HDA)
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